Proportion of bronchopulmonary dysplasia in extreme preterm babies after updated management strategies: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Proportion of extreme preterms with BPD
研究概览
简要总结
Number of premature births worldwide is on the rise; fortunately, so is survival. Prospective, recent, regional data regarding clinically relevant and patient oriented outcomes of those ≤ 28 weeks are sparse. It is a fact that peri-viable and extreme preterm neonates require intensive care, high supports and specialized practices for long durations. Health care planners and parents need to prepared for these implications. Data on outcomes of babies who still requires respiratory support at 36 weeks post menstrual age and also data regarding the associated risk factors and co-morbidities and their management would drive policies. These would aid parent counselling and help in planning of resource allocation.
Our unit has reported >60% survival overall in this group. We have been providing intensive care supports after shared decision making even for periviable gestation. This study is aimed at analysis of incidence and risk factors of bronchopulmonary dysplasia of extreme preterms (≤ 28 weeks) after the unit updated practice policies for this high-risk group.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0.00 Day(s) 至 60.00 Day(s)(—)
- 性别
- All
入选标准
- •All preterm neonates born during the study period between 22 to 28 weeks of gestation (inborn; or out-born referred within 24 hours of life) at birth who are offered standard care; and complete care in the unit till time point of measurement of primary outcome.
排除标准
- •Babies who were transferred out before completion of care; whose primary outcome is not retrievable after transfer.
- •Babies with major congenital malformations requiring surgical intervention during hospital stay.
- •3.Those preterm infants between 22-23 weeks who were offered comfort care after shared decision making.
结局指标
主要结局
Proportion of extreme preterms with BPD
时间窗: at 36 weeks of post menstrual age
次要结局
- 1. To compare the BPD rates between 2 groups: After updated policy (2024-2026) with the cohort who received care in 2020-2022 (before the care policy was updated)(2. In the study group, to analyse:)
研究者
Nabagata Roy
Kerala Institute of Medical sciences
