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A Study of the Efficacy of RWJ-333369 in the Prevention of Migraine

Phase 2
Completed
Conditions
Migraine Headaches
Registration Number
NCT00109083
Lead Sponsor
SK Life Science, Inc.
Brief Summary

The purpose of this study is to evaluate whether RWJ-333369 is a safe and effective treatment in reducing the number of migraine headaches when added to a person's usual medications for acute migraine headache relief.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
300
Inclusion Criteria
  • Established history of migraines for at least 1 year;
  • Have between 3 and 12 migraine attacks per month, and no more than 15 headache days in total per month;
  • Migraines must have first started before age 50.
Exclusion Criteria
  • Most frequent headache type is not migraine;
  • Failed 3 or more studies of effective migraine-preventing medications;
  • Overuse of pain medications to treat migraines;
  • Not willing to stop use of migraine-preventing medications;
  • Significant serious concomitant diseases.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Percent reduction in the average monthly migraine frequency from the baseline period to the entire double-blind treatment phase.
Secondary Outcome Measures
NameTimeMethod

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