Simulation of Adenosine Push Methods for Treatment of SVT Using Agitated Saline Visualized by Ultrasound

Not Applicable

Completed

• Conditions: Supraventricular Tachycardia
• Interventions: Other: Agitated saline push

• Registration Number: NCT04051541
• Lead Sponsor: HealthPartners Institute

Brief Summary

Supraventricular tachycardia (SVT) is an abnormally fast heart rhythm arising from improper electrical activity in the upper part of the heart. SVT is commonly treated with adenosine using three different IV administration techniques. However, it is not well known which of these three techniques is the quickest or most likely to reach the heart in order to stop SVT. This study will simulate each of those techniques in an investigator-blinded procedure. Intravenous agitated saline, used as a surrogate for a dose of adenosine, will be administered to healthy volunteers using all three techniques and monitored using bedside ultrasound to observe their efficacy and speed in reaching the right side of the heart.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-05-06
• Primary Completion: 2019-06-28
• Study Completion: 2019-06-28
• Status Verified: 2019-08
• Study First Submitted: 2019-08-07
• Study First Submitted QC: 2019-08-07
• Study First Posted: 2019-08-09
• Last Update Submitted: 2023-06-28
• Last Update Posted: 2023-07-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Volunteers aged 18 years and older
• Able to understand and provide signed consent for the study
• Must be healthy; not being actively treated for any condition that requires active medical intervention or monitoring to avert serious danger to the participant's health or well-being, as evaluated by study investigator

Exclusion Criteria

• Non-English speaker
• Those with contraindications to peripheral IV placement, such as infection or other contraindication noted from evaluation by study investigator
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Simulation arm	Agitated saline push	All patients were entered into the Simulation arm and received 3 pushes of agitated saline via 3 different methods of delivery. All patients received all methods. The order of the methods for each patient was randomized.

Primary Outcome Measures

Name	Time	Method
Time to ultrasound visualization of agitated saline in the right heart	<5 seconds	Time from IV push to ultrasound visualization of agitated saline in the right heart

Trial Locations

Locations (1)

Regions Hospital; 🇺🇸 Saint Paul, Minnesota, United States