Comparative Study of Adityapaka Guggulu with Janu Basti and Sandhivatari Gutika with Janu Basti in the Management of Janusandhigata Vata with special reference to Osteoarthritis of Knee Joint
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Patients of either sex of 30 to 60 years old diagnosed as Janu sandhigata vata (Osteoarthritis of knee joint) will be selected for relief in sign and symptoms.
研究概览
简要总结
Osteoarthritis isthe most prevalent form of arthritis in India, affecting over 15 million adultsevery year. It is the disease of old age and by 2020, the number of 65 yearsand above population in India is likely to be about 177 million. India maybecome the osteoarthritis capital of the world with over 60 million cases ofthe diseases by 2025. Despite the advancement in using new drugs and techniques, the management ofOsteoarthritis with analgesics, corticosteroids and surgical procedure (totalknee replacement) in Allopathic medicine is either temporary or very costly andalso having many side effects. Ayurvedais the best alternative option. In Ayurveda,Sandhigata Vata is managed by Snehana, Swedana, Upanaha and Vata Shamak drugs. Among the widevarieties of drugs mentioned in Ayurvedatext books, Adityapaka Guggulu and Sandhivatari Gutika have been chosen forthe study so as to re-establish their efficacy which may contribute to thesuccessful treatment of Sandhigata Vata(OA). Adityapaka guggulu which has been mentioned invVatavyadhiprakaran of Chakradatta contains triphala, pipplai, tvak, elaand guggulu processed in dashmool kvatha. Similarly, SandhivatariGutika which has been mentioned in Uttarkhanda, Amavata Chikitsha ofRasachandansu contains rakta bola, hingula and guggulu. Thecontents of these drugs are easily available and cheaper. They are easy to useas there is no special measure or precaution that needs to be taken duringtheir administration. The efficacy of these two drugs will be assessed and compared.In both cases Janu Basti with Nirgunditailam will also be done.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •i.Patient willing to sign the consent form.
- •ii.Patients between the ages of 30-60 years of either sex.
- •iii.Patients with signs and symptoms of Janusandhigata Vata.
- •iv.Patients with OA changes in X-ray.
- •v.Patients with chronicity of less than 5 years.
排除标准
- •i.Patients suffering from paralysis.
- •ii.Patients of rheumatoid arthritis, gout, ankylosing spondylitis and traumatic arthritis.
- •iii.Patients having septic arthritis, tuberculosis, brucellosis, pyogenic osteomyelitis, etc.
- •iv.Patients having malignancy and other complicated diseases like Congestive Cardiac Failure (CCF), Diabetes Mellitus, Malignant Hypertension, etc.
- •v.Patients having severe osteoarthritic changes.
- •vi.Patients with bony deformity.
- •vii.Pregnant and lactating mother.
结局指标
主要结局
Patients of either sex of 30 to 60 years old diagnosed as Janu sandhigata vata (Osteoarthritis of knee joint) will be selected for relief in sign and symptoms.
时间窗: 30 days
次要结局
- to compare the efficacy of Adityapaka Guggulu with Janu Basti and Sandhivatari Gutika with Janu Basti in the Management of Janusandhigata Vata with special reference to Osteoarthritis of Knee Joint.(30days)