Preliminary study: Safety and Immunological Response following COVID-19 Vaccination in COVID-19 survivors
- Conditions
- COVID-19 survivorsCOVID-19 Vaccination
- Registration Number
- TCTR20210720005
- Lead Sponsor
- Faculty of Medicine Siriraj Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 180
1. Males or females at least 18 years of age (inclusive)
2. Had a history of SARS-CoV-2-positive by RT-PCR from airway specimens at screening day (10+/-4 weeks or 20+/-4 weeks after detection)
3. Can understand Thai language through speaking, reading and writing
4. Able to communicate through electronic tools such as Google form or line
5. Capable of attending all study visits according to the study schedule
6. Capable of informed consent and provision of written informed consent before any study procedures
1. Have history of severe drug or vaccine allergy (anaphylaxis)
2. Have received blood transfusion, plasma, blood product, blood components, immunoglobulins, antiviral or antibodies within the last 90 days
3. Have history of cigarettes smoking, alcohol drinking and history of drug abuse
4. Be pregnant
5. Have history of any vaccination within 14 days before screening visit
6. Had received more than one COVID-19 vaccination before diagnosis of COVID-19 infection
7.Had received any COVID-19 vaccination after Yes
diagnosis of COVID-19 infection
8. Have unstable disease or could not control the symptom
9.Have history of immunodeficiency or use immunosuppressant or steroid drugs?
10. Have any unusual symptoms or medical history that considered unable to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adverse events 4 weeks amount of adverse events
- Secondary Outcome Measures
Name Time Method Immune response 24 weeks Immune response level