MedPath

A Pilot Study: Safety and Immunological Response following Intradermal COVID-19 vaccination with Accelerate Regime

Phase 1
Conditions
Healthy volunteer
COVID-19
vaccine
safety
immunological response
intradermal
Accelerate Regimen
Registration Number
TCTR20210904004
Lead Sponsor
Health Systems Research Institute (HSRI)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
60
Inclusion Criteria

1. Males or females at least 18-60 years of age (inclusive)
2. Have not received any COVID-19 vaccine?
3. Can understand Thai language through speaking, reading and writing?
4. Able to communicate through electronic tools such as Google form or line?
5. Capable of attending all study visits according to the study schedule.
6. Capable of informed consent and provision of written informed consent before any study procedures.

Exclusion Criteria

1. Have history of severe drug or vaccine allergy (anaphylaxis)?
2. Have detected COVID-19 infection?
3. Have history of COVID-19 high risk contact?
4. Have history of Chronic respiratory disease, CVD, CKD, CVS, obesity, cancer and DM?
5. Positive result(s) from either antigen test kit.
6. Have received blood transfusion, plasma, blood product, blood component, immunoglobilins, antiviral or antibodies within the last 90 days?
7. Have history of cigarettes smoking, alcohol drinking and history of drug abuse?
8. Being pregnant?
9. have unstable disease or could not control the sysptom?
10. Have history of immunodeficiency or been using immunosuppressant or steriod drugs?
11. Have any unusual symptoms or medical history that considered unable to participate in the study?

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Immunological Response 2 wk and 12 wk after complete vaccination IgG level
Secondary Outcome Measures
NameTimeMethod
Safety 7 days after vaccination Adverse effects
© Copyright 2025. All Rights Reserved by MedPath