A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients
- Conditions
- Acute Stroke
- Interventions
- Other: Observational study, no intervention
- Registration Number
- NCT05454397
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Brief Summary
Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management. Early and full tube feeding in the acute phase of stroke helps to address nutritional problems resulting from dysphagia and impaired consciousness and helps to reduce morbidity and mortality and poor outcomes. Current guidelines for acute stroke management do not address the goal of tube feeding of enteral nutrition for energy and protein. In the treatment of acute stroke, there is a strong global focus on pharmacological thrombolysis or mechanical thrombolysis, with nutritional interventions being a less explored topic. Real-world evidence on large samples, feeding attainment and outcomes, and nutrition in the acute phase of stroke is lacking in China . The aim of this study was to understand the current status of nutritional therapy in stroke hospitalization in neurology and its impact on prognosis nationwide, and to improve the standardized management process of enteral nutrition therapy in the acute phase of stroke.
- Detailed Description
Malnutrition is a common geriatric syndrome with a disproportionate incidence in geriatric and neurology inpatients. In recent years, national nutritional surveys of geriatric inpatients have shown that about 2/3 of geriatric inpatients have nutritional problems; only half of neurology inpatients at high risk receive nutritional support, and inadequate nutrition exacerbates primary disease, increases complications, makes hospital stays longer, and ultimately affects patient survival outcomes.
To increase comprehensive and up-to-date research on the current status of nutritional therapy in geriatric and neurology inpatients, and to lay the foundation for future standardized treatment and standardized management, we conducted a nationwide survey on the current status of nutritional risk screening and treatment in geriatric and neurology inpatients. The aim is to raise the level of clinicians' awareness of malnutrition and nutritional risk in hospitalized patients, standardize clinical practice, and properly implement nutritional support to improve patients' clinical outcomes.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 2000
- Newly admitted stroke patients admitted to neurology, age ≥18 years, within 7 days of onset, expected survival >3 months (i.e., not end-stage), expected neurology stay 7-10 days；
- At risk of malnutrition (MUST ≥ 2 points) or at nutritional risk (NRS2002 ≥ 3 points), sign an informed notice.
- Transferred during treatment, contraindications to nutritional therapy (e.g., hemodynamic instability, gastrointestinal bleeding (bleeding >100 ml), other nutritional studies, pregnancy.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description case group Observational study, no intervention Patients with acute stroke with nutritional risk
- Primary Outcome Measures
Name Time Method Nutrition compliance rate of stroke inpatients The first day of admission； the seventh day of admission； the day before discharge. Percentage of patients hospitalized for stroke whose nutritional indicators and nutritional status met the guidelines after being given nutritional support
Nutrition implementation rate The first day of admission； the seventh day of admission； the day before discharge. Proportion of patients hospitalized for stroke who were given nutritional support
- Secondary Outcome Measures
Name Time Method Infection rate 30-day post-discharge Proportion of enrolled patients with pulmonary infection 30 days after discharge from hospital.
Functional prognosis 30-day post-discharge Functional prognosis of the enrolled patients, such as life skills, motor and sensory functions, cognitive functions and swallowing functions.
30-day post-discharge mortality 30-day post-discharge Proportion of enrolled patients who died 30 days after discharge from the hospital
Readmission rate 30-day post-discharge Proportion of patients enrolled who were readmitted for various reasons 30 days after discharge.
Trial Locations
- Locations (34)
The First People'S Hospital of Kunshan
🇨🇳Kunshan, Jiangsu, China
Qilu Hospital of Shandong University(Qingdao)
🇨🇳Qingdao, Shandong, China
Red Cross Hospital of Hangzhou
🇨🇳Hangzhou, Zhejiang, China
The First People'S Hospital of Wenling
🇨🇳Wenling, Zhejiang, China
Dongfang Hospital of Beijing University of Chinese Medicine
🇨🇳Beijing, Beijing, China
The First Affiliated Hospital of Anhui Medical University
🇨🇳Hefei, Anhui, China
The First Afilliated Hospital of Fujian Medical University
🇨🇳Fuzhou, Fujian, China
Fujian Province Zhangzhou Hospital
🇨🇳Zhengzhou, Fujian, China
Zhongshan Hospital Xiamen University
🇨🇳Xiamen, Fujian, China
Kaifeng Central Hospital
🇨🇳Kai Feng, Henan, China
Tongji Hospital of Tongji Medical College of HUST
🇨🇳Wuhan, Hubei, China
The First Affiliated Hospital of Guangxi Medical University
🇨🇳Nanning, Guangxi, China
The second Affiliated Hospital of Harbin Medical University
🇨🇳Ha'erbin, Heilongjiang, China
Nanfang Hospital of Southern Medical University
🇨🇳Guangzhou, Guangdong, China
Nanjing Zijin Hospital
🇨🇳Nanjing, Jiangsu, China
Henan Provincial People'S Hospital
🇨🇳Zhengzhou, Henan, China
Xiangya Hospital Central South University
🇨🇳Changsha, Hunan, China
Zhongda Hospital Southeast Universtiy
🇨🇳Nanjing, Jiangsu, China
The second Affiliated Hospital of Suzhou University
🇨🇳Suzhou, Jiangsu, China
Ganzhou People'S Hospital
🇨🇳Ganzhou, Jiangxi, China
Yancheng Third People's Hospital
🇨🇳Yancheng, Jiangsu, China
The First Hospital of Jilin University
🇨🇳Changchun, Jilin, China
Qilu Hospital of Shandong University
🇨🇳Jinan, Shandong, China
Affiliated Hospital of Jining Medical Hospital
🇨🇳Jining, Shandong, China
Linyi People'S Hospital
🇨🇳Linyi, Shandong, China
The Affiliated Hospital of Qingdao University
🇨🇳Qingdao, Shandong, China
Yantai Yuhuangding Hospital
🇨🇳Yantai, Shandong, China
Chongqing People's Hospital
🇨🇳Chongqing, Sichuang, China
The First Affiliated Hospital of Xi'an Jiaotong University
🇨🇳Xi'an, Shanxi, China
Xi'an Encephalopathy of Traditional Chinese Medicine Hospital
🇨🇳Xi'an, Shanxi, China
The First People'S Hospital of Jiashan
🇨🇳Jiaxing, Zhejiang, China
Zhejiang Province Xiaoshan Hospital
🇨🇳Hanzhou, Zhejiang, China
The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU
🇨🇳Wenzhou, Zhejiang, China
Wenzhou Hospital of Chinese Medicine
🇨🇳Wenzhou, Zhejiang, China