跳至主要内容
临床试验/NCT05494554
NCT05494554
已完成
不适用

Comparison of Mechanical Power Calculations of Volume Control and Pressure Control Modes: A Prospective Observational Study

Bakirkoy Dr. Sadi Konuk Research and Training Hospital1 个研究点 分布在 1 个国家目标入组 36 人2020年1月1日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Ventilator-Induced Lung Injury
发起方
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
入组人数
36
试验地点
1
主要终点
Mechanical power values of different ventilation modes
状态
已完成
最后更新
3年前

概览

简要总结

The management of ARDS, which is one of the important problems of intensive care patients, has gained popularity with the pandemic. Mechanical ventilation is an important life-saving treatment in ARDS patients. However, when not used correctly, it can cause Ventilator-Induced Lung Injury (VILI). Therefore, lung protective ventilation should be applied to minimize VILI in ARDS patients. Mechanical power is one of the parameters that guides intensivist in predicting VILI.

详细描述

The goal of mechanical ventilation in ARDS patients is to improve oxygenation by reducing the work of breathing . With this aim, the orientation towards sensitive ventilation strategies has increased in the light of experience and scientific data from the past to the present. Today, the concept of Mechanical Power (MP) has been developed, which combines different variables, such as tidal volume, drive pressure, gas flow, respiratory rate, and PEEP, which have been associated with VILI in various studies, into a single parameter. In this study, the investigators used the simplified MP equation (MPvcv (simpl)) developed by Gattinoni et al. for power calculation in volume control mode and the simplified MP equation (MPpcv(simpl)) developed by Becher et al. for power calculation in pressure control mode. Thus, the investigators aimed to compare the volume control and pressure control modes over the concept of MP.

注册库
clinicaltrials.gov
开始日期
2020年1月1日
结束日期
2022年1月22日
最后更新
3年前
研究类型
Observational
性别
All

研究者

发起方
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
责任方
Sponsor

入排标准

入选标准

  • Patients with confirmed Covid-19 diagnosis in intensive care unit (ICU) and diagnosed with ARDS according to Berlin criteria
  • Intubated patients which treated in the supine position on the second day of ICU admission

排除标准

  • Patients with a known diagnosis of COPD
  • Patients experiencing hemodynamic instability during ventilation
  • Prone pozisyonda olan hastalar
  • Patients receiving inotropic support
  • Patients with missing data

结局指标

主要结局

Mechanical power values of different ventilation modes

时间窗: 60 minutes

We aimed to compare the volume control and pressure control modes over the mechanical power values.

研究点 (1)

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