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Clinical Trials/NCT06525922
NCT06525922
Completed
N/A

Center M Feasibility and Efficacy Pilot Study

Oregon Health and Science University1 site in 1 country87 target enrollmentAugust 4, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Perinatal Depression
Sponsor
Oregon Health and Science University
Enrollment
87
Locations
1
Primary Endpoint
Edinburgh Postnatal Depression Scale (EPDS)
Status
Completed
Last Updated
last year

Overview

Brief Summary

The goal of this pilot study is to evaluate the acceptability, feasibility, mechanisms of action, and efficacy of Center M. Center M is a group-based, mindfulness-based Cognitive Behavioral Therapy (CBT) intervention to treat Perinatal Depression (PD).

Detailed Description

The goal of this pilot study is to evaluate the acceptability, feasibility, mechanisms of action, and efficacy of Center M. Center M is a group-based, mindfulness-based Cognitive Behavioral Therapy (CBT) intervention to treat Perinatal Depression (PD). Pregnant participants will be surveyed at three time points: pre-intervention, post-intervention, and 6-weeks postpartum. Surveys will include self-report measures evaluating depressive symptoms, mindfulness skills, emotion regulation, and participant satisfaction.

Registry
clinicaltrials.gov
Start Date
August 4, 2021
End Date
March 13, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ellen Tilden

Principal Investigator

Oregon Health and Science University

Eligibility Criteria

Inclusion Criteria

  • gestational age at intervention onset between 12 and 30 weeks
  • English fluency
  • no previous experience in a mindfulness-based intervention group
  • ability and willingness to participate in a telehealth intervention

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Edinburgh Postnatal Depression Scale (EPDS)

Time Frame: Measured at pre-intervention (within 1 week before first session), post-intervention (within 1 week after last session), and 6-weeks postpartum

10-item self-report measure used to assess perinatal depression symptomology over the past seven days.

Emotional Regulation Questionnaire (ERQ)

Time Frame: Measured at pre-intervention (within 1 week before first session) and 6-weeks postpartum

10-item self-report measure used to assess one's ability to regulate or manage emotion using cognitive reappraisal and expressive suppression.

Five Facets of Mindfulness Questionnaire (FFMQ)

Time Frame: Measured at pre-intervention (within 1 week before first session) and 6-weeks postpartum

39-item self-report measure to assess mindfulness skills.

Patient Health Questionnaire - 8 (PHQ-8)

Time Frame: Measured at pre-intervention (within 1 week before first session), post-intervention (within 1 week after last session), and 6-weeks postpartum

Self-report measure that assesses depressive symptoms over the past two weeks.

Secondary Outcomes

  • ERQ Expressive Suppression Subscale(Measured at pre-intervention (within 1 week before first session) and 6-weeks postpartum)
  • ERQ Cognitive Reappraisal Subscale(Measured at pre-intervention (within 1 week before first session) and 6-weeks postpartum)
  • Center M Satisfaction(Post-intervention (within 1 week after last session))

Study Sites (1)

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