Comparison of the detection rate in SPECT/CT with NaI detectors and SPECT/CT with CZT semiconductor detectors used in bone scintigraphy - RAD324

Not Applicable

• Conditions: Bone metastases; C79.5; Secondary malignant neoplasm of bone and bone marrow

• Registration Number: DRKS00011421
• Lead Sponsor: niversitätsklinikum Magdeburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-20
• Study Completion: 2020-01-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Presence of an indication for bone scintigraphy in malignancy
• Patient age > 18 years
• normal renal function
• No contraindications for a second examination sequence (e.g., claustrophobia, poor general state)

Exclusion Criteria

• no compliance for the second examination
• Suspected of benign bone disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
on-inferiority of a detector technology:<br><br>Comparing the detection rates of pathological bone metabolism between two different SPECT/CT systems used in imaging of bone metabolism by (1) planar whole body imaging and (2) SPECT/CT.

Secondary Outcome Measures

Name	Time	Method
(1.) Comparison of readers confidence in whole body image quality<br>(2.) Comparison of readers confidence in SPECT/CT image quality and alignment of morphologic structures