The Effect of Remifentanil on Rebound Pain in Patients Receiving General Anesthesia for Shoulder Arthroplasty After Brachial Plexus Block for Postoperative Pain Control
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Total infused dose of patient controlled analgesia(PCA) drug during 24 hours
研究概览
简要总结
The investigators will evaluate the influence of intraoperative remifentanil infusion on the postoperative hyperalgesia in patients receiving rotator cuff repair after brachial plexus block for postoperative analgesia.
详细描述
The study will include 68 patients undergoing rotator cuff repair. All patients will receive brachial plexus block for postoperative analgesia, followed by general anesthesia. In the experimental group, remifentanil infusion will not be used intraoperatively, and in the control group, remifentanil will be infused. After surgery, both groups will be given the same postoperative pain management using patient controlled analgesia(PCA), and pain patterns will be assessed using the Numerical rating scale (NRS) at 4 hour intervals for 24 hours. The primary end point of this study is the total dose of PCA medication over 24 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA class I,II,III
- •Patients undergoing arthroscopic rotator cuff repair surgery under general anesthesia after interscalen brachial plexus block for post operative analgesia
- •Age ranges from 20 to 70
排除标准
- •Patients who didn't agree to study
- •Patients can't control PCA(Patient-Controlled-Analgesia) independently
- •Patients who have conciousness disorder or can't express their pain level by NRS(Numeric Rating Scale) system
- •Patients who have severe respiratory disease or hepatic failure
- •Patinets who have known neuropathy or coagulopathy
- •Pregnancy
- •Patients with allegies to the drugs used in this study
研究组 & 干预措施
not used intraoperative remifentanil infusion
Adult patients aged < 70 years and ASA class < III undergoing rotator cuff repair not used intraoperative remifentanil infusion
干预措施: Not used remifentanil infusion (Drug)
结局指标
主要结局
Total infused dose of patient controlled analgesia(PCA) drug during 24 hours
时间窗: From end of operation to the 24hours after operation
Total infused dose of patient controlled analgesia(PCA) drug during first 24 hours after rotor cuff repair under general anesthesia
次要结局
- Total patient's trial to PCA bolus infusion(24 hours after surgery)
- Numerical Ratings Scale(Pain levels are checked using Numerical Ratings Scale at 4 hour intervals for 24 hours after surgery)
- Incidence of postoperative nausea and vomiting(24 hours after surgery)
研究者
Jin-Tae Kim
Professor
Seoul National University Hospital