The Effect of Remifentanil Infusion During Emergence on the Incidence of Emergence Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Remifentanil
- Conditions
- Delirium
- Sponsor
- Yeungnam University College of Medicine
- Enrollment
- 86
- Locations
- 1
- Primary Endpoint
- the scale of emergence agitation
- Last Updated
- 10 years ago
Overview
Brief Summary
The aim of the present study is to assess the effect of postoperative remifentanil infusion on the incidence of emergence agitation in preschool-aged children undergoing strabismus surgery with sevoflurane anaesthesia.
Detailed Description
Patients are randomly assigned to one of two groups. Anesthesia is maintained with sevoflurane and remifentanil infusion. All patients received a predetermined concentrations of remifentanil according to their group assignments (control group, remifentanil 0 ug/kg/min; remifentanil group, remifentanil 0.05 ug/kg/min) from 10 minutes before the end of surgery to discharge from postanesthetic care unit. emergence agitation is assessed during the emergence phase.
Investigators
Sangjin Park
assistant professor
Yeungnam University College of Medicine
Eligibility Criteria
Inclusion Criteria
- •American Society of Anesthesiologists physical status I and II
- •preschool-aged children undergoing strabismus surgery
Exclusion Criteria
- •psychological disorders
- •emotional disorders
- •abnormal cognitive development
- •developmental delay
- •allergy to the drugs in our protocol
Arms & Interventions
remifentanil group
Remifentanil 0.05 ug/kg/min is infused to the patients.
Intervention: Remifentanil
control
Normal saline 0.2 ml/kg/hour is infused to the patients
Intervention: Placebo
Outcomes
Primary Outcomes
the scale of emergence agitation
Time Frame: up to 30 minutes after arrival in postanesthetic care unit, and 30 minutes after discharge from postanesthetic care unit.
A blinded observer record emergence agitation at just after laryngeal mask removal, 5 minutes after arrival in postanesthetic care unit, 10 minutes after arrival in postanesthetic care unit, 15 minutes after arrival in postanesthetic care unit, 30 minutes after arrival in postanesthetic care unit, and 30 minutes after discharge from postanesthetic care unit.
Secondary Outcomes
- the effect of remifentanil on the emergence(up to 30 minutes after the discharge form postanesthetic care unit)