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RFA for Small HCC With No-touch Technique Using Octopus Electrode

Not Applicable
Completed
Conditions
Carcinoma, Hepatocellular
Registration Number
NCT02832882
Lead Sponsor
Seoul National University Hospital
Brief Summary

In this study, the investigators are going to prospectively compare the clinical outcomes (technical success rate, 12 month local tumor progression rate, complication rate, tumor seeding rate) of Radiofrequency ablation (RFA) with octopus electrode and no-touch technique for Hepatocellular carcinoma (HCC) to those of RFA with conventional tumor puncture method with the same device.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
118
Inclusion Criteria
  • Child-Pugh class A
  • patient with 1cm-2.5cm sized HCC
  • 1 or 2 HCCs
  • being referred for curative purpose of RFA
  • sign informed consent
Exclusion Criteria
  • maximum tumor diameter greater than 2.5cm
  • Child-Pugh class B or C
  • more than 3 HCC lesions
  • invisible tumor even after US/CT or US/MR fusion
  • presence of vascular tumor thrombosis or extrahepatic metastasis
  • severe coagulopathy (PLT < 50K, PT < 50% of normal range)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
12 month local tumor progression (LTP) rate12 month after RFA
Secondary Outcome Measures
NameTimeMethod
tumor seeding rate12 months after RFA

incidence of tract seeding after RFA.

Technical success rate1 months

presence or absence of residual lesion on follow-up imaging

Complication rate related with RFA1 month

RFA-related complication rate such as death, abscess, bleeding..etc.

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