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Clinical Trials/NCT06028750
NCT06028750
Completed
Not Applicable

Accuracy of Dental Implant Placement Using Dynamic Navigation or the Freehand Method: a Randomized Controlled Clinical Trial in Novice Operators

University of Barcelona1 site in 1 country60 target enrollmentSeptember 8, 2023
ConditionsDental Implants

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dental Implants
Sponsor
University of Barcelona
Enrollment
60
Locations
1
Primary Endpoint
To evaluate in novice surgeons the accuracy of the X-Guide® navigation system (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) in implant placement compared to freehand implant placement.
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

The purpose of the study is to evaluate in novice surgeons the accuracy of the X-Guide® navigation system (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) in implant placement compared to freehand implant placement.

Detailed Description

Randomized clinical trial with 2 parallel treatment groups. Eligible patients will be randomized with a 1:1 ratio to one of 2 possible parallel treatment groups: * Group 1: Nobel Replace Conical Connection® placed freehand. * Group 2: Nobel Replace Conical Connection® placed using the X-Guide guided surgery system (X-Nav Technologies®, Pennsylvania, USA). PRIMARY OBJECTIVE: - To evaluate in novice surgeons the accuracy of the X-Guide® Navigation System (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) in implant placement compared to freehand implant placement. SECONDARY OBJECTIVES: * To evaluate overall surgical time with the X-Guide® Navigation System (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) compared to freehand implant placement in inexperienced surgeons. * To evaluate Patient Reported Outcomes Measures (PROMs) during implant treatment with navigation systems performed by novice surgeons.

Registry
clinicaltrials.gov
Start Date
September 8, 2023
End Date
November 1, 2024
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Octavi Camps-Font

Associate Professor of Oral Surgery

University of Barcelona

Eligibility Criteria

Inclusion Criteria

  • Subjects who agree to voluntarily sign the informed consent before performing any action related to the study.
  • Men or women at least 18 years old.
  • Single edentulous spaces or edentulous sections located in maxilla or mandible with a healing period longer than 12 weeks to rehabilitate with implant-supported fixed crowns ≤3 units.
  • O'Leary plaque and/or bleeding on probing index ≤25%.

Exclusion Criteria

  • Systemic diseases that may interfere with dental implant placement.
  • Any contraindications for oral surgical procedures.
  • History of head and neck radiotherapy.
  • Patients smoking \>20 cigarettes/day or tobacco equivalents.
  • History of substance abuse (drugs or alcohol) or any other factor (e.g., severe psychiatric illness) that, in the opinion of the investigator, could interfere with the patient's ability to cooperate and comply with the study.
  • Patients who have participated in a clinical trial within the last 30 days.
  • Pregnant or lactating women.
  • Patients with poor or unmotivated oral hygiene.
  • Probing depth with bleeding of ≥4 mm in one of the teeth adjacent to the edentulous space or tract.
  • Need to perform guided bone regeneration procedures simultaneous to implant placement.

Outcomes

Primary Outcomes

To evaluate in novice surgeons the accuracy of the X-Guide® navigation system (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) in implant placement compared to freehand implant placement.

Time Frame: Through study completion, an average of 1 year.

The accuracy of placement of Nobel Replace Conical Connection® implants (Nobel Biocare) will be evaluated by superimposing the two cone-beam computed tomography (CBCT) (pre- and post-surgical) and calculating the deviations from the pre-operative planning and the final implant position. The superimposition of both CBCTs will be performed using X-Guide Standalone Planning Software (Nobel Biocare). The following variables will be analyzed for each implant: Angular deviation, Lateral platform deviation (2D), Global platform deviation (3D), Lateral apex deviation (2D), Apex depth deviation and Global apex deviation (3D).

Secondary Outcomes

  • Comparison of Patient Reported Outcomes Measures (PROMs) between navigated and freehand surgery, using the Oral Health Impact Profile questionnaire, in addition to a PROMs questionnaire designed.(The OHIP-14 will be performed just before starting the surgery and at the 7-day postoperative control. The PROMs questionnaire will be performed by the patient just after finishing the implant surgery and having explained the postoperative instructions.)
  • Comparison of postoperative pain between navigated and freehand surgery, using a questionnaire designed with a visual analog scale (VAS).(The postoperative pain will be evaluated immediately after the surgery with a VAS questionnaire and during the 7 days following surgery.)
  • To evaluate overall surgical time with the X-Guide® Navigation System (X-Guide®, X-Nav Technologies®, Pennsylvania, USA) compared to freehand implant placement in inexperienced surgeons.(During the surgical procedure.)

Study Sites (1)

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