europhysiological and molecular biological investigations into sensory processing of chronic pruritus with cutaneous and non-cutaneous causes in the cowhage model (Pruri-Cow) - PruriCow

IZKF der medizinischen Fakultät der Universität Münster0 个研究点目标入组 160 人开始时间: 2013年8月14日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. only control subjects: History taking on atopic disposition (us-ing Erlangener atopy criteria), presence of pruritus
•2. skin lesions in the area to be investigated (e.g. erosions, infections, acute exacerbation, cutaneous infections in atopic dermatitis),
•3. neurological and psychiatric diseases in the patient history or currently suffering from the disease
•4. skin type > III (mediterranean, dark and black skin type),
•5. allergy to substances used /ingredients of the cream,
•6. disorders preventing participation in the investigation,
•7. intake of a drug, which influences the pruritus perception within the 2 weeks before examination
•8. use of urea, polidocanol, menthol, capsaicin, topical steroids, topical keratolytics, exfoliators, self-tanning, topical or systemic antihistamines, naltrexon, anticonvulsants, sedatives within the 2 weeks before examination
•9. systemic steroids, UV-therapy within the 4 weeks before examination
•10. topical or systemic immunomodulators, antidepressants, anti-migraine medications within the 2 months before examination
•11. NSAIDs and other analgesics 7 days before examination,
•12. drug consumption, medication abuse,
•13. cosmetic and skin care products in the area to be investigated on the day of examination,
•14. participation in another investi-gation within the past 4 weeks
•15. pregnancy, nursing mother

发起方

IZKF der medizinischen Fakultät der Universität Münster