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Clinical Trials/DRKS00005226
DRKS00005226
Completed
Not Applicable

europhysiological and molecular biological investigations into sensory processing of chronic pruritus with cutaneous and non-cutaneous causes in the cowhage model (Pruri-Cow) - PruriCow

IZKF der medizinischen Fakultät der Universität Münster0 sites160 target enrollmentAugust 14, 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
L29.9
Sponsor
IZKF der medizinischen Fakultät der Universität Münster
Enrollment
160
Status
Completed
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 14, 2013
End Date
January 18, 2016
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
IZKF der medizinischen Fakultät der Universität Münster

Eligibility Criteria

Inclusion Criteria

  • chronic pruritus in
  • atopic dermatitis (AD; sub\-acute, chronic)
  • OR brachioradial pruritus (BRP)
  • OR prurigo nodularis (PN)
  • controls (no atopic disposition, no dermatoses)

Exclusion Criteria

  • 1\. only control subjects: History taking on atopic disposition (us\-ing Erlangener atopy criteria), presence of pruritus
  • 2\. skin lesions in the area to be investigated (e.g. erosions, infections, acute exacerbation, cutaneous infections in atopic dermatitis),
  • 3\. neurological and psychiatric diseases in the patient history or currently suffering from the disease
  • 4\. skin type \> III (mediterranean, dark and black skin type),
  • 5\. allergy to substances used /ingredients of the cream,
  • 6\. disorders preventing participation in the investigation,
  • 7\. intake of a drug, which influences the pruritus perception within the 2 weeks before examination
  • 8\. use of urea, polidocanol, menthol, capsaicin, topical steroids, topical keratolytics, exfoliators, self\-tanning, topical or systemic antihistamines, naltrexon, anticonvulsants, sedatives within the 2 weeks before examination
  • 9\. systemic steroids, UV\-therapy within the 4 weeks before examination
  • 10\. topical or systemic immunomodulators, antidepressants, anti\-migraine medications within the 2 months before examination

Outcomes

Primary Outcomes

Not specified

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