Effect Of Tranexamic acid By Microneedling in Melasma.
Phase 3
- Conditions
- Melasma..
- Registration Number
- IRCT20180811040761N1
- Lead Sponsor
- Kerman University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 30
Inclusion Criteria
All Women with Melasma.
Exclusion Criteria
Coagulopathy Disease.
Hormone Therapy.
Topical treatment, like Hydroquinone, in the past year.
Active Herpes.
Facial Wart.
Hypersensivity to Tranexamic acid & Hydroquinone.
Pregnancy and Lactation.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Melasma intensity based on MASI (Melasma Area Severity Index ) score. Timepoint: (Melasma Area Severity Index ) MASI Score measurement at the beginning of the study and weeks 4, 8,12. Method of measurement: Using the Melasma Area Severity Index (MASI) Score.;The rate of recovery of melasma lesions based on the Patient Global Assessment. Timepoint: The rate of improvement of melasma lesions at the end of the study was based on the Patient Global Assessment questionnaire. Method of measurement: Patient Global Assessment Questionnaire.;The rate of recovery of melasma lesions based on the Patient Global Assessment. Timepoint: The rate of improvement of melasma lesions at the end of the study was based on the Physician Global Assessment questionnaire. Method of measurement: Physician Global Assessment Questionnaire.
- Secondary Outcome Measures
Name Time Method