Imaging of brain inflammation in Muay Thai boxers

• Conditions: n/a; Therapeutic area: Not possible to specify

• Registration Number: EUCTR2012-004785-18-NL
• Lead Sponsor: niversity Medical Center Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01-09
• Last Update Posted: 1 December 2014

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

All subjects:
-Age above 18 and below 50 years
-Male sex
-Written informed consent for participation

Boxers only:
-Minimum amount of 20 competitive bouts in Muay Thai boxing with rank A or B
-Minimum amount of 3 training sessions per week

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

All subjects:
-The use of benzodiazepines.
-The use of anticoagulants or having coagulation disorder.
-Use of somatic medication that may affect the immune system.
-Use of any investigational drug.
-Current or recent (<1 year) alcohol or substance abuse.
-Current or recent (<4 weeks) infectious or inflammatory disease.
-Current systemic disease.
-Major metabolic disease.
-Somatic, organic or neurological disorder (other than mTBI for patients).
-Participation in a scientific research study (<1 year) involving radiation.
-Claustrophobia.
-Presence of materials in the body that can be magnetized.
-Sustained (mild) traumatic brain injury within last 3 months.

For healthy volunteers only:
-Presence of infection of inflammation.
-(History of) Participation in contact sports, such as boxing, Muay Thai boxing, rugby, American football, etc.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified