Comparative study of different infusion rates of oxytocin in elective caesarean section.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To measure the total estimated blood loss (EBL) in intraoperative period after the infusion of 5U/h and 2.5 U/h of oxytocin during elective caesarean section under spinal anaesthesia.
研究概览
简要总结
Oxytocin is the most commonly used uterotonic agent in obstetrics. It is routinely administered after both normal and operative delivery to initiate and maintain adequate uterine contractility for minimizing blood loss and preventing postpartum haemorrhage. Several regimens of oxytocin have been tested during caesarean delivery (CD) with variable wanted and unwanted effects. Since appropriate dose of oxytocin has not been established this study will be carried out with aim to compare effects of low dose oxytocin given as IV bolus plus infusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •Pregnant patients undergoing elective caesarean section in spinal anaesthesia will be included in the study.
- •Uncomplicated, singleton pregnancy
- •ASA class 1 & 2.
排除标准
- •Patients with multiple pregnancies
- •Complicated pregnancies, risk factors for postpartum haemorrhage (PPH)
- •Contraindication to spinal anaesthesia and
- •Patients in active labour.
结局指标
主要结局
To measure the total estimated blood loss (EBL) in intraoperative period after the infusion of 5U/h and 2.5 U/h of oxytocin during elective caesarean section under spinal anaesthesia.
时间窗: Intraoperative period
次要结局
- To measures the following after the administration of oxytocin:(1. Adequacy of uterine tone.)