Efficacy of a Dietary Supplement on Parameters of Skin Aging in Men and Women
- Conditions
- Skin Aging
- Interventions
- Dietary Supplement: HyaCera™Dietary Supplement: Placebo
- Registration Number
- NCT06083402
- Lead Sponsor
- Natals, Inc. dba Ritual
- Brief Summary
As the body ages, the skin experiences natural changes in structure and composition. These changes may manifest visibly as increased skin dryness, wrinkling, and a loss of firmness/elasticity. In this double-blind, randomized, placebo-controlled trial, the investigators will recruit healthy men and women with mild to moderate signs of skin aging and randomly assign them to either receive a HyaCera™ or placebo for 12 weeks. The investigators will perform a series of objective and subjective measurements to assess changes in skin condition. The investigators hypothesize that consumption of HyaCera™ leads to improvements in the general condition of the skin including skin hydration, crow's feet wrinkling, and other skin aging parameters.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 63
- Healthy male and female volunteers, 25 - 70 years old with mild to moderate fine lines and wrinkles
- All ethnicities and skin types
- Willing to maintain current skincare regimen on face, arms, and legs and withhold all facial and body treatments throughout the course of the study
- Self-reported pregnant or breastfeeding or planning to become pregnant during the course of the study
- Any conditions on the face, arms and legs that would interfere with evaluations
- Under treatment for any known health issues/medical conditions including chronic health conditions and skin diseases/conditions
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Active HyaCera™ Participants receive 1 HyaCera™ capsule orally once daily for 12 weeks Placebo Placebo Participants receive 1 placebo capsule orally once daily for 12 weeks
- Primary Outcome Measures
Name Time Method Crow's Feet Wrinkles at week 0, Week 4, Week 8, and Week 12 Degree of crow's feet wrinkling will be measured via Visioscan®
Skin Smoothness at week 0, Week 4, Week 8, and Week 12 Skin smoothness will be measured via Visioscan®
Skin Hydration at week 0, Week 4, Week 8, and Week 12 Skin surface hydration will be measured via Corneometer® 825
- Secondary Outcome Measures
Name Time Method Skin Elasticity at week 0, Week 4, Week 8, and Week 12 Skin elasticity will be measured via Cutometer® MPA 580
Skin Scaliness at week 0, Week 4, Week 8, and Week 12 Skin scaliness will be measured via Visioscan®
Skin Barrier Function at week 0, Week 4, Week 8, and Week 12 Skin barrier function (as transepidermal water loss) will be measured via Tewameter®
Trial Locations
- Locations (1)
Princeton Consumer Research
🇺🇸Raritan, New Jersey, United States