The effect of position (sit/stand up vs supine position) on urge sensation in volunteers and in patients with overactive bladder syndrome
- Conditions
- overactive bladder syndromeurgency10018188
- Registration Number
- NL-OMON35512
- Lead Sponsor
- Academisch Ziekenhuis Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Patient arm: patients older than 18 years with OAB diagnosed by their urologist using the criteria of more than 8 micturitions on three consecutive days of these three days they keep a micturation diary with a VAS score for urge sensation. Patients should have at least one episode of urge: sudden compelling desire to void which can not be postponed.
Volunteers arm: volunteers older than 18 years are considered eligible if they have no urologic history or urinary complaints.
Patient arm: congestive heart disease or history of heart failure; patients on anticholinergic medication that are not willing to stop this medication; presence of post void residual urine > 100cc determined by ultrasound; presence of urinary tract infection, determined by urine sticks. Patients with urinary tract infection will be treated by antibiotics. After resolution of the infection, the patient can re-enter the study if the urine is sterile at that moment.
Volunteer arm: urinary complaints or urologic history; congestive heart disease or history of hear failure; presence of postvoid residual urine > 100cc determined by ultrasound; presence of urinary tract infection, determined by urine sticks. Volunteers that present with urinary tract infection will be definitively excluded from participation.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>· To study the effect of position on bladder sensation in volunteers and<br /><br>patients with overactive bladder syndrome<br /><br>· To study the effect of position on voided volumes in volunteers and patients<br /><br>with overactive bladder syndrome<br /><br>· To study the relationship between bladder sensation and the voided volumes in<br /><br>both volunteers and patients.<br /><br><br /><br></p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary objectives<br /><br><br /><br>· To characterise self consciousness in patients with OAB<br /><br>· To characterise the difference between volunteers and patients with OAB in<br /><br>regards to self consciousness and bladder perceptions<br /><br>· To characterise the difference between men and women in regards to self<br /><br>consciousness and bladder perceptions.<br /><br>· To determine the relationship between self-consciousness and bladder<br /><br>perceptions in patients with OAB<br /><br>· To determine the relationship between the functional bladder capacity and OAB<br /><br>symptoms in relation to patient perception<br /><br>· To relate voided volumes to patient perception.<br /><br>· To study the link between OAB symptoms and patient bother from OAB to self<br /><br>consciousness and bladder perception<br /><br>· To study the relationship between the functional and maximal bladder capacity<br /><br>in relation to OAB symptoms and bother in OAB patients. </p><br>