Effect of steroids on blood sugar levels and risk of heart disease in pituitary patients

Not Applicable

Recruiting

• Conditions: Secondary adrenal insufficiency; Hypopituitarism; Metabolic and Endocrine - Other metabolic disorders

• Registration Number: ACTRN12612000234819
• Lead Sponsor: Dr Morton Burt

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-02-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Hydrocortisone less than or equal to 20mg per day (or other glucocorticoid at equivalent dose)
GC use for at least 6 months
Age greater than or equal to 20 years

Exclusion Criteria

Atrial fibrillation
Beta blocker medication
Raynaud’s phenomenon
Inability to provide written informed consent
On treatment for diabetes

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint is the change in pulse wave velocity with higher glucocorticoid dose, assessed by paired t-tests.[After increased glucocorticoid dose for 7 days]