The Comparison of Dexmedetomidine and Midazolam for the Sleep in Intensive Care Unit
- Conditions
- Sleep Arousal DisordersPoor Quality SleepSleep DeprivationDelirium
- Registration Number
- NCT01966315
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
The investigators are going to compare the sleep quality and quantity between dexmedetomidine group and midazolam group using 24 hour polysomnography in critically ill patients. And the investigators also compare the incidence of delirium between the two groups.
- Detailed Description
Sleep is very important for cognitive and immune function. However, patients in intensive care unit (ICU) have a very poor sleep.
Almost all ventilated patients in intensive care unit (ICU) take a sedative drug. In Korea, most commonly used sedative drugs are dexmedetomidine and midazolam.
The investigators are going to compare the sleep quality and quantity between dexmedetomidine group and midazolam group using 24 hour polysomnography. And the investigators also compare the incidence of delirium between the two groups.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 5
- sedation patients with dexmedetomidine or midazolam
- over 18 years old
- Neurologic disease (stroke, seizure, dementia, hypoxic brain damage)
- Brain infection
- Alcoholics
- Major Depression Disorder, Schizophrenia, Anxiety disorder
- Hearing loss
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The differences of sleep stage, sleep efficiency, arousal index and delirium between dexmedetomidine group and midazolam group during ICU stay
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Seoul National University Bundang Hospital
🇰🇷Seongnam-si, Gyeonggi-do, Korea, Republic of