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Clinical Trials/NCT05574179
NCT05574179
Not yet recruiting
Early Phase 1

Comparison of Sedative Effect of Dexmedetomidine and Midazolam for TIVA in Pediatric Population Undergoing Inguinal Hernia Repair, Randomized Controlled Trial

Sheikh Zayed Medical College0 sites60 target enrollmentJanuary 1, 2023
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ConditionsChoosing Better Drug Option for Sedation in Pediatric Population Intraoperatively
InterventionsMidazolamDexmedetomidine injection
DrugsDexmedetomidine injectionMidazolam

Overview

Phase
Early Phase 1
Intervention
Midazolam
Conditions
Choosing Better Drug Option for Sedation in Pediatric Population Intraoperatively
Sponsor
Sheikh Zayed Medical College
Enrollment
60
Primary Endpoint
Dexmedetomidine is better sedative agent than midazolam in pediatric population
Status
Not yet recruiting
Last Updated
3 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSimilar Trials

Overview

Brief Summary

Comparison of sedative effects of dexmedetomidine and midazolam using ramsay sedation scores intraoperatively in children undergoing inguinal hernia repair.

Detailed Description

a randomized controlled trial to compare the sesative effects of dexmedetomidine and midazolam in pediatric population planned for inguinal herna repair under TIVA in sheikh zayed hospital rahim yar khan.

Registry
clinicaltrials.gov
Start Date
January 1, 2023
End Date
October 31, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Barzah Durrani

Dr Barzah durrani

Sheikh Zayed Medical College

Eligibility Criteria

Inclusion Criteria

  • •ASA I and II Age 6 to 12 years Any gender

Exclusion Criteria

  • •ASA III and above Age less than 2 years and above 12 years Congenital heart disease Cardiac arrythmias Congenital abnormalities Respiratory disease Endocrine disorders Mental retardation Organ dysfunction Bleeding disorders Physician or family refusal Previous surgeries Allergy to any drug

Arms & Interventions

midazola.

Inj.midazolam

Intervention: Midazolam

Dexnedetomidine

inj.dexmedetomidine

Intervention: Dexmedetomidine injection

Outcomes

Primary Outcomes

Dexmedetomidine is better sedative agent than midazolam in pediatric population

Time Frame: 25 minutes

Secondary Outcomes

  • Midazolam is better sedating agent than dexmedetomidine in pediatric population(25 minutes)
  • Midazolam and dexmedetomidine are equally good sedating agents in pediatric population(25 minutes)

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