COVID19 Chronic Morbidity: Follow-up of patients with COVID19 and non-COVID19 pneumonia with respect to clinical status, pulmonary function and radiologic findings

Recruiting

• Conditions: Coronavirus Disease 19 (COVID19); U07.1; J12; J13; J14; J15; J16; J17; J18; COVID-19, virus identified

• Registration Number: DRKS00022475
• Lead Sponsor: niversitätsklinikum Frankfurt

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

Patients after SARS-CoV2 infection or community-acquired pneumonia
- age >= 18 years
- written informed consent

Exclusion Criteria

- pregnancy
- for non-COVID19 pneumonia: hospitalisation >48h prior to diagnosis

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
As the long-term consequences of COVID19 are not yet known, this study is intended as an exploratory analysis of different aspects. A formal separation into primary and secondary outcome measures will therefore not be made. <br>The following aspects will be investigated in this study<br><br>- Oxygenation (Horovitz index 1,3,6,9, and 12 months after diagnosis)<br>- static/dynamic lung volumes<br>- gas exchange (capillary blood gas analysis, diffusing capacity, total oxygen uptake, total oxygen uptake during spiroergometry)<br>- symptoms (e.g., 18-item community-acquired pneumonia symptom questionnaire, dyspnoea [mMRC scale])<br>- occurence of exacerbations of previously known pulmonary disases (COPD, asthma, ILD)<br>- medication<br>- quality of life (36-item short form survey)<br>- development of pathogen-specific antibodies<br><br>

Secondary Outcome Measures

Name	Time	Method
/ (see above)