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GENENTECH, INC.

GENENTECH, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

Clinical Trials

766

Active:256
Completed:407

Trial Phases

5 Phases

Phase 1:378
Phase 2:153
Phase 3:67
+2 more phases

Drug Approvals

44

FDA:40
PHILIPPINES:2
SFDA:2

Drug Approvals

OCREVUS

Approval Date
Aug 25, 2025
FDA

TECENTRIQ

Approval Date
Aug 22, 2025
FDA

Columvi

Approval Date
Jun 18, 2025
FDA

Xofluza

Approval Date
Jun 16, 2025
FDA

POLIVY

Approval Date
Apr 2, 2024
FDA

XOLAIR

Approval Date
Feb 22, 2024
FDA

CellCept

Approval Date
Feb 21, 2024
FDA

Pulmozyme

Approval Date
Feb 16, 2024
FDA

Rozlytrek

Approval Date
Feb 6, 2024
FDA

Valcyte

Approval Date
Jan 11, 2024
FDA
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Clinical Trials

Distribution across different clinical trial phases (642 trials with phase data)• Click on a phase to view related trials

Phase 1
378 (58.9%)
Phase 2
153 (23.8%)
Phase 3
67 (10.4%)
Phase 4
24 (3.7%)
Not Applicable
20 (3.1%)

A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

Not Applicable
Not yet recruiting
Conditions
Hepatic Impairment
Interventions
First Posted Date
2025-08-27
Last Posted Date
2025-08-27
Lead Sponsor
Genentech, Inc.
Target Recruit Count
32
Registration Number
NCT07144111

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

Not Applicable
Recruiting
Conditions
Breast Cancer
Interventions
First Posted Date
2025-08-03
Last Posted Date
2025-08-26
Lead Sponsor
Genentech, Inc.
Target Recruit Count
285
Registration Number
NCT07100106
Locations
🇺🇸

New York Cancer & Blood Specialists, East Patchogue, New York, United States

A Study to Evaluate the Relative Bioavailability of Two Tablet Formulations Compared to Capsule Formulation and the Effect of Food and Proton Pump Inhibitor on ZN-A-1041 Tablet(s) in Healthy Participants

Not Applicable
Recruiting
Conditions
Healthy Participants
Interventions
First Posted Date
2025-07-04
Last Posted Date
2025-08-26
Lead Sponsor
Genentech, Inc.
Target Recruit Count
66
Registration Number
NCT07051993
Locations
🇬🇧

Fortrea Leeds CRU, Leeds, United Kingdom

A Study to Assess the Tolerability and Safety of Subcutaneously (SC) Administered Immunoglobulin G (IgG) With Varying Injection Conditions

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2025-06-17
Last Posted Date
2025-09-10
Lead Sponsor
Genentech, Inc.
Target Recruit Count
82
Registration Number
NCT07025577
Locations
🇺🇸

Daytona Beach Clinical Rsch Unit, Daytona Beach, Florida, United States

🇺🇸

Fortrea Clinical Research Unit - Dallas, Dallas, Texas, United States

🇺🇸

Fortrea Clinical Research Unit Inc. - Madison, Madison, Wisconsin, United States

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, and Pharmacodynamics of P-CD19CD20-ALLO1 in Participants With Multiple Sclerosis

Not Applicable
Not yet recruiting
Conditions
Multiple Sclerosis
Interventions
Biological: P-CD19CD20-ALLO1 Cells
First Posted Date
2025-06-06
Last Posted Date
2025-08-12
Lead Sponsor
Genentech, Inc.
Target Recruit Count
60
Registration Number
NCT07008378
Locations
🇺🇸

UC Irvine, Sue & Bill Gross Stem Cell Research Center, Irvine, California, United States

🇺🇸

UC San Diego, Altman Clinical and Translational Research Institute, La Jolla, California, United States

🇺🇸

University of South Florida, Tampa, Florida, United States

and more 10 locations
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News

Tryptase Inhibitor Fails to Meet Primary Endpoint in Asthma Exacerbation Trial

A Phase 2a clinical trial of MTPS9579A, an anti-tryptase antibody, did not significantly reduce the time to first asthma exacerbation event compared to placebo.

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