NL-OMON49014已完成不适用
Enhancing the BCG-induced trained immunity response by addition of bisphosphonate or MMR vaccine: a possible preventive approach against COVID-19 (BCG-PLUS) - Enhancing the BCG-induced TI via bisphosphonates or MMR vaccine
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* Adult (18-50 years of age);
- •* Male or female;
- •* Healthy;
- •* Written informed consent
排除标准
- •* Known allergy to (components of), or any other contraindication to, the BCG
- •vaccine, MMR vaccine, or alendronic acid.
- •* Known (history of) active or latent Mycobacterium tuberculosis or with
- •another mycobacterial species;
- •* Prior BCG vaccination;
- •* Acute illness 2 weeks prior to the study or (suspicion of) active infection;
- •* Pregnancy;
- •* Chronic use of any systemic drugs other than oral contraceptives;
- •* Use of NSAIDs less than 4 weeks prior to start of the study;
- •* Vaccination in the past 3 months or expected vaccination during the study
- •period, independent of the type of vaccination;
- •* Medical history associated with immunodeficiency.
研究者
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