Anti-inflammatory enzymes for pain reduction and rapid wound healing in postoperative tonsillectomy

Phase 2

• Conditions: post-operative tonsillectomy pain and wound healing; tonsillectomy, lysozyme chloride

• Registration Number: TCTR20240723009
• Lead Sponsor: Choomit 1967 Co., Ltd.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-23
• Last Update Posted: 19 August 2024
• Study Completion: 2025-08-31

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1.Age 18-65 years
2.The participants must have met the indication for tonsillectomy

Exclusion Criteria

1. The participants have contraindication for surgery such as take antiplatelet medication or bleeding condition from genetic disease
2. Have contraindication for general anesthesia
3. Have underlying disease that reduce wound healing
4. Have history of RT/CCRT
5. Using steroid or immunotherapy drug
6. The participants have contraindication for acetaminophen, ibuprofen
7. The participants have contraindication for lysozyme chloride and egg white
8. Pregnancy of Lactation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Wound healing 1,2,3,7,14 days Percent of epithelialization of tonsillar bed

Secondary Outcome Measures

Name	Time	Method
Pain 1,2,3,7,14 days Pain score by visual analog scale