Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/JPRN-UMIN000014360
JPRN-UMIN000014360CompletedPhase 2

Venous sac embolization for pulmonary arteriovenous malformations using Hydrocoils: a phase II study (SCIRO-1402) - Venous sac embolization for pulmonary arteriovenous malformations using Hydrocoils (SCIRO-1402)

Okayama University Hospital0 sites21 target enrollmentStarted: July 1, 2014Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditions

Trial Snapshot

Phase
Phase 2
Status
Completed
Enrollment
21
Study OverviewEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Embolization was successfully completed in 20/21 pulmonary arteriovenous malformations (PAVMs). A technical failure occurred in one PAVM, where embolization was abandoned because of migration of one bare coil to the left ventricle. One patient with one PAVM was lost to follow-up after 3 months. Neither recanalization nor reperfusion was noted in the remaining 19 PAVMs (success rate, 19/19 [100%]). One grade 4 (coil migration) adverse event occurred, and it was treated without any sequelae.

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
20years-old to ot applicable (—)
Sex
All

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • •1) History of allergy of iodinated contrast material 2) Active asthma 3) Single lung. 4) Inpaired pulmonary function of contralateral lung. 5) Pulmonary hypertension. 6) Estimated Glomerular Filtration Rate < 30min/mil (excluding dialysis) 7) Child Pugh score >= 9 8) Heart failure (NYHA >= III) 9) Uncontrolable malignant disease. 10) Active infection or active inflammatory process 11) Body temperature of 38 degree or more. 12) Pregnant. 13) Not eligible determined by the responding physician.

Investigators

Similar Trials

Recruiting
Not Applicable
Pulmonary arteriovenous malformations: strategies for detection, treatment and follow-up.Hereditary haemorrhagic telangiectasia (HHT)Trans thoracic contract echocardiography (TTCE)Pulmonary arteriovenous malformations (PAVMs)Magnetic resonance imaging (MRI)Computed tomography (CT)
NL-OMON25616St. Antonius Hospital1,500
Withdrawn
Not Applicable
Contrast Echocardiography in Patients With Pulmonary Arteriovenous Malformations (PAVMs)Pulmonary Arteriovenous Malformations
NCT00733759Imperial College London
Completed
Not Applicable
A new way of treating patients with respiratory failure
ISRCTN31262122Belfast Health & Social Care Trust412
Completed
Not Applicable
Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMsPulmonary Arteriovenous MalformationsHereditary Hemorrhagic Telangiectasia
NCT02436213Imperial College London39
Unknown
Not Applicable
Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs With and Without Airflow ObstructionPulmonary Arteriovenous MalformationsCOPDAsthmaHereditary Hemorrhagic Telangiectasia
NCT02458703Imperial College London60