Reversibility of Esophageal Dysmotilities Associated With Gastric Banding After Conversion to Gastric Bypass
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- reversibility of dysmotility after surgery
研究概览
简要总结
In the current study we plan to evaluate the effects of the conversion from gastric banding to gastric bypass on esophageal function using combined monitoring. The primary aim of the current study is to evaluate esophageal function before and 3-months after the conversion from gastric banding to gastric bypass. A second objective is to evaluate the severity of symptoms, esophageal dysmotilities, endoscopic abnormalities and bolus retention found in patients referred for conversion from gastric banding to gastric bypass. Our hypothesis is that esophageal motility disorders associated with gastric banding are reversed by conversion to gastric bypass.
详细描述
2.2.3 Research plan
As model for this study we propose a longitudinal single-center study design with testing before and after the surgical intervention.
Participants
The study population will be limited to patients considered for gastric banding to gastric by-pass conversion. Patients will be recruited from the surgical out-patient clinic
Testing during the study period
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients in whom a conversion from gastric band to gastric bypass is planed
排除标准
- •Acute cardiac or pulmonary conditions
- •Antireflux surgery or antireflux endoscopic procedures.
- •Patients unable to provide informed consent
结局指标
主要结局
reversibility of dysmotility after surgery
时间窗: 3 months
次要结局
- degree of dysmoztility after gastric banding(not defined)