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临床试验/NCT02357641
NCT02357641已完成不适用

Analysis of Myocardial Deformation in Patients With Acute Coronary Disease

RWTH Aachen University1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2013年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
300
试验地点
1
主要终点
Determination of cut off value of circumferential and radial myocardial echographic strain data corresponding to acute coronary disease

研究概览

简要总结

Examination of probable distinction between cardiac or non- cardiac thoracal disorder via echocardiographic myocardial strain analysis

详细描述

Patients with cardiac disorder have to undergo time- consuming and expensive examinations such as laboratory of cardiac biomarkers or ischemic diagnostic. To save time and money in this observational registry the probable distinction between cardiac and non- cardiac disorder in patients with vague thoracal disorder and the probability for coronary artery disease (determined via Grace Score) is examined via echographic myocardial strain analysis in 300 patients retrospectively to establish a cut off value corresponding to acute coronary disease also to prevent coronary angiography. Therefore patients undergo echography routinely with consecutive evaluation of systolic, diastolic and strain analysis to elevate exact statements with reference to deformation of the myocard and its velocity. Several study have shown that these strain parameters (circumferential and radial strain) enable vitality and ischemic diagnosis and therefore could be eligible for this purpose.

研究设计

研究类型
Observational
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • thoracal cardiac or non cardiac disorder
  • signed informed consent

排除标准

  • glomerular filtration rate (GFR) < 60 ml/min
  • angina pectoris
  • acute myocardial infarction within 3 months prior inclusion
  • pregnancy

结局指标

主要结局

Determination of cut off value of circumferential and radial myocardial echographic strain data corresponding to acute coronary disease

时间窗: 1 year

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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