Myocardial deformation imaging to assess subclinical myocardial dysfunction in patients with metabolic dysfunction associated steatotic liver disease(MASLD) and its correlation with liver stiffness measurement. - NI

Kasturba Medical College Manipal0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年3月4日

试验速览

暂无简介。

•Metabolic dysfunction associated steatotic liver disease(MASLD) defined as presence of hepatic steatosis by imaging(USG )or biopsy with atleast one of the cardiometabolic criteria which includes
•BMI more than 25 kg/m2 or WC more than 94 cm in males or 80 cm in
•FBS more than 100, PPBS more than 200,HBA1C more than 5.7 or known case of T2DM
•BP more than 130/85mmhg
•Plasma triglyceride more than 170 mg/dl
•Plasma HDL less than 40mg/dl in males HDL less than 50mg/dl in females
•Age less than 65 years and more than 18 years
•Average daily alcohol intake less than 20g/day female, less than 40gm/day in males

•age more than 65 years and less than 18 years
•daily alcohol intake on more than 20g/day in female, more than 40g/day in male
•diagnosis of cirrhosis at histology or at clinical ground
•presence of hepatocellular carcinoma, ascites, portal hypertension; other comorbid liver diseases (autoimmune hepatitis, HBV, HCV, alcoholic liver disease)
•atrial fibrillation; left bundle branch block; history of coronary artery disease (previous myocardial infarction, previous percutaneous coronary intervention or previous coronary artery bypass graft)
•moderate-to-severe mitral and/or aortic valve disease; hypertrophic, infiltrative and/or dilated cardiomyopathy
•history of congenital heart disease
•left ventricular ejection fraction (LVEF)less than 50%
•acute coronary syndrome, acute congestive heart failure, acute respiratory failure, acute renal failure
•hemodynamic instability
•poor echocardiographic acoustic windows (not adequate for appropriate visualization and definition of endocardial border of all cardiac chambers)
•lack of consent

发起方