Strain-Encoded Magnetic Resonance Imaging in Acute Myocardial Infarction
- Conditions
- Acute Myocardial Infarction
- Interventions
- Procedure: cardiac MRI
- Registration Number
- NCT00752713
- Lead Sponsor
- RWTH Aachen University
- Brief Summary
The aim of the study was therefore to evaluate whether myocardial deformation imaging performed by SENC allows for quantification of regional left ventricular function and is related to transmurality states of infarcted tissue in patients with acute myocardial infarction (AMI).
- Detailed Description
CMR was performed in 38 consecutive patients with AMI 3±1 days after successful reperfusion using a clinical 1.5 Tesla MR-scanner. Ten healthy volunteers served as controls. SENC is a technique that directly measures peak circumferential strain from long-axis views and peak longitudinal strain from short axis views. Measurements were obtained for each segment in a modified 17 segment model. Wall motion and infarcted tissue were evaluated semi-quantitatively from SSFP cine sequences and contrast-enhanced-MR-images and were then related to myocardial strain. Comparison of peak circumferential strain assessed by SENC and MR-tagging was performed.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
- Patients with AMI after successful reperfusion
- Healthy volunteers in control group
- No reperfusion
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 1 cardiac MRI Patients presenting to hospital with AMI 2 cardiac MRI healthy volunteers as control group
- Primary Outcome Measures
Name Time Method Left ventricular function 01.01.2007 until 01.02.2007
- Secondary Outcome Measures
Name Time Method Transmurality 01.01.2007 until 01.02.2007
Trial Locations
- Locations (1)
University Hospital Heidelberg
🇩🇪Heidelberg, Germany