Role of Stress CMR in Predicting Adverse Clinical Events in Patients With Known or Suspected Ischemic Heart Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- Brigham and Women's Hospital
- Enrollment
- 2347
- Locations
- 2
- Primary Endpoint
- A composite outcome measure consisting of cardiovascular mortality and nonfatal MI after index CMR.
- Status
- Completed
- Last Updated
- 5 months ago
Overview
Brief Summary
The investigators plan to use retrospective data to assess heart function and structure abnormalities through the use of an approved vasodilating agent for stress cardiac MRI tests. The investigators are interested in how these MRI findings relate to long-term prognosis in people who are at risk for cardiac disease.
Investigators
Raymond Y. Kwong, MD
Principal Investigator
Brigham and Women's Hospital
Eligibility Criteria
Inclusion Criteria
- •Age \>/= 21 years old
- •No contraindications for cardiac MRI (by renal function or metallic hazards)
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
A composite outcome measure consisting of cardiovascular mortality and nonfatal MI after index CMR.
Time Frame: target follow up of at least 4 years
"Myocardial infarction" will be defined as hospital admission for acute coronary syndrome (defined by positive serum troponin level with documented electrocardiographic changes, clinical syndrome, or need for percutaneous or surgical revascularization).
Secondary Outcomes
- A composite outcome measure consisting of cardiovascular mortality, nonfatal MI, hospitalization for unstable angina or congestive heart failure, and late unplanned coronary bypass surgery at at least 6 months after index CMR.(target follow up of at least 4 years)