Detecting Early Myocardial Infiltration w/Amyloid & Light Chain Deposition Disease in Multiple Myeloma Subjects
Terminated
- Conditions
- Multiple Myeloma
- Interventions
- Device: Administering three additional MRI images
- Registration Number
- NCT01018927
- Lead Sponsor
- University of Arkansas
- Brief Summary
The purpose of this study is to see if MRI techniques can be used for early evaluation of cardiac amyloidosis which is sometimes seen in individuals with multiple myeloma. Cardiac amyloidosis is a medical disorder that decreases heart function.
- Detailed Description
The purpose is to investigate the use of multiple newer CMR techniques for early evaluation of cardiac amyloidosis in multiple myeloma.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
- All races and ethnic groups
- Male and female ages 18-80 years of age
- History of multiple myeloma
- CMR study for evaluation for cardiac amyloidosis
Exclusion Criteria
- Pregnant women
- Subject with a metallic or electronic or other device that could be affected by the magnet
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Additional MRI images Administering three additional MRI images Prospective review of 100 CMR studies performed on multiple myeloma patients referred for cardiac evaluation by MRI. Three additional MRI images will be performed to determine the role of cardiac MR (CMR) in detecting features of early myocardial infiltration
- Primary Outcome Measures
Name Time Method This study is to see if MRI techniques can be used for early evaluation of cardiac amyloidosis which is sometimes seen in individuals with multiple myeloma. The time frame is five additional minutes & three additional images during and MRI.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University or Arkansas for Medical Sciences (UAMS)
🇺🇸Little Rock, Arkansas, United States