NCT05047029已完成不适用
Multiparametric Magnetic Resonance Imaging in Patients With Liver Cirrhosis for Evaluation of Myocardial Fibrosis and Inflammation in Cirrhotic Cardiomyopathy
University Hospital, Bonn2 个研究点 分布在 1 个国家目标入组 13 人开始时间: 2018年11月2日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Myocardial T1 relaxation time
研究概览
简要总结
The aim of this clinical prospective study is to assess structural and functional myocardial changes in patients with liver cirrhosis after implantation of transjugular intrahepatic portosystemic shunt (TIPS).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Myocardial T1 relaxation time
时间窗: Change after 1 year of transjugular intrahepatic portosystemic shunt insertion.
T1 relaxation times will be obtained to asses acute myocardial injury and fibrosis. T1 maps will be analyzed using a segmental approach by region of interest analysis. T1 relaxation times are given in \[ms\].
次要结局
- Myocardial T2 relaxation time(Change after 1 year of transjugular intrahepatic portosystemic shunt insertion.)
- Myocardial ECV(Change after 1 year of transjugular intrahepatic portosystemic shunt insertion.)
研究者
Julian Alexander Luetkens
Prinicipal Investigator, Senior Physician
University Hospital, Bonn
研究点 (2)
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