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临床试验/NCT05047029
NCT05047029已完成不适用

Multiparametric Magnetic Resonance Imaging in Patients With Liver Cirrhosis for Evaluation of Myocardial Fibrosis and Inflammation in Cirrhotic Cardiomyopathy

University Hospital, Bonn2 个研究点 分布在 1 个国家目标入组 13 人开始时间: 2018年11月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
13
试验地点
2
主要终点
Myocardial T1 relaxation time

研究概览

简要总结

The aim of this clinical prospective study is to assess structural and functional myocardial changes in patients with liver cirrhosis after implantation of transjugular intrahepatic portosystemic shunt (TIPS).

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Myocardial T1 relaxation time

时间窗: Change after 1 year of transjugular intrahepatic portosystemic shunt insertion.

T1 relaxation times will be obtained to asses acute myocardial injury and fibrosis. T1 maps will be analyzed using a segmental approach by region of interest analysis. T1 relaxation times are given in \[ms\].

次要结局

  • Myocardial T2 relaxation time(Change after 1 year of transjugular intrahepatic portosystemic shunt insertion.)
  • Myocardial ECV(Change after 1 year of transjugular intrahepatic portosystemic shunt insertion.)

研究者

发起方
University Hospital, Bonn
申办方类型
Other
责任方
Principal Investigator
主要研究者

Julian Alexander Luetkens

Prinicipal Investigator, Senior Physician

University Hospital, Bonn

研究点 (2)

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