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临床试验/NCT04425395
NCT04425395招募中不适用

The Effect of Nonverbal Vocalisations on Pain Tolerance

Centre Hospitalier Universitaire de Saint Etienne2 个研究点 分布在 1 个国家目标入组 104 人开始时间: 2022年5月11日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
104
试验地点
2
主要终点
Pain tolerance

研究概览

简要总结

Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions.

and important social issues. Yet despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal vocalizations remain little studied and poorly understood including in humans. In this context, the investigators wish to examine how the production of vocalizations non-verbal communication influences pain tolerance in healthy adults.

详细描述

Humans produce nonverbal vocalisations such as screams, grunts, roars, cries and laughter across a variety of contexts. Yet despite the prominence and apparent importance of these nonverbal sounds in human communication, the investigators still know very little about their influence on human perception and behaviour. That's why, in this study, the investigators will examine specifically the influence of nonverbal vocal production on pain tolerance.

The remainder of the study will involve up to three trials of a pain tolerance (cold pressor) task, during which the investigators will ask participants to produce vocalisations (e.g., screams or words) while submerging the participant's hand in bath of circulating cold water.

The results of the study will contribute to our theoretical understanding of the functions of nonverbal vocal communication in humans, in particular the influence of nonverbal vocal production (i.e., yelling) on pain tolerance.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Participant in good health
  • Affiliated or entitled participant in a social security scheme
  • Participant who has received informed information about the study and has co-signed a consent to participate in the study with the investigator.

排除标准

  • Chronic pain
  • High blood pressure or poor circulation
  • Cardiac or vascular disease, or a heart condition (including symptoms of Raynaud's syndrome)
  • Allergy or hypersensitivity to cold
  • Pregnancy
  • Recent serious injury
  • Neurological or psychiatric condition known to affect pain tolerance (e.g., peripheral neuropathy, schizophrenia)
  • History of fainting or seizures
  • History of frostbite
  • Chronic smoker (more than 10 cigarettes a day)

结局指标

主要结局

Pain tolerance

时间窗: at inclusion

Delay (in seconds) in removing the hand when testing the Cold Pressor.

次要结局

  • Pain intensity(at inclusion)
  • Analysis of Acoustic Recordings(at inclusion)
  • Onset of pain(at inclusion)
  • correlation between NOL index and pupillary diameter(at inclusion)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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