Methods of abortion in second trimester

Phase 4

Not yet recruiting

Conditions: Obstetrics,

Registration Number: CTRI/2022/09/046065

Lead Sponsor: Dr Hanumant V Nipanal

Brief Summary: Abortion is defined asTermination of pregnancy by any means before the fetus is viable. Abortionswill be done up to 24 weeks pregnancy Medical Termination of Pregnancy [MTP]Act, enacted by the Indian parliament came into effect from 1 April 1972 andnew amendment of 2021. Presently MTP can be performed on Medical,Eugenic, Humanitarian and Social grounds, Terminatinga pregnancy in 2nd trimester is a bigger danger to boththe mother and foetus as compared to a first trimester pregnancy. A majority ofthe abortions in second trimester are carried out because of foetalabnormalities and sometimes maternal complications. Out of the differentmethods of termination, medical methods are believed to be safer and moreeffective as compared to the surgical approaches. Intravaginal misoprostol andintracervical Foley catheter are the most preferred methods. Few researchersclaim intravaginal misoprostol whereas others believe intracervical Foleycatheter to be more effective and few researches have speculated that if theboth methods are combined will give best results.

Hence,our study is aimed to compare the efficacy of misoprostol versus combination ofFoley catheter and misoprostol in second trimester medical termination ofpregnancy.**OBJECTIVES:**To Comparethe efficacy of misoprostol versus Foley and misoprostol combination in secondtrimester medical termination of pregnancy.

**Datacollection method:** Pregnant women attending theOPD of GIMS for second trimester MTP that is 12+1 weeks to 24 weeks ofgestation and who will fulfil inclusion and exclusion criteria were selectedfor the study. Ultrasound examination was used for the date confirmation andtheir eligibility to enter into the study. Selected patients were admitted toobstetrics ward and procedure will be planned. Complete evaluation of each patientwas done at admission. Detailed history as well as clinical findings of medicaland obstetric examination was recorded.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 96

Inclusion Criteria

All cases those who will fulfil indication of Medical Termination of Pregnancy for second trimester up 24 weeks, as per guidelines of MTP Act of 1971 and amended in 2021.

Exclusion Criteria

Scarred uterus 2.
Ectopic pregnancy 3.
Grand multipara 4.
Contraindications to misoprostol and Foleys catheter.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Complete expulsion of products of conception	24hours

Secondary Outcome Measures

Name	Time	Method
complications (if any)	48 hours

Trial Locations

Locations (1): Gadag Institute of Medical sciences Gadag
🇮🇳
Gadag, KARNATAKA, India
Gadag Institute of Medical sciences Gadag
🇮🇳Gadag, KARNATAKA, India
Dr Hanumant V Nipanal
Principal investigator
9448001054
hanumantvn.1210@gmail.com