Pathophysiology of urge incontinence in older wome
Completed
- Conditions
- rge incontinence, detrusor hyperreflexia with impaired contractility (DHIC)Urological and Genital DiseasesUrge incontinence
- Registration Number
- ISRCTN17856439
- Lead Sponsor
- ational Institutes of Health (USA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 250
Inclusion Criteria
Cognitively intact, community-dwelling persons at least 55 years old with urge incontinence at least every two days
Exclusion Criteria
1. Significant stress incontinence
2. Outlet obstruction
3. Post-voiding residual (PVR) urine >300 ml
4. Mini mental state examination (MMSE) <24/30
5. Inability to go to the toilet independently
6. Contraindication to antimuscarinic therapy
7. Gastrointestinal obstruction
8. Megacolon
9. Severe liver or renal disease
10. Uncontrolled hyperthyroidism
11. Multiple sclerosis
12. Anteroposterior resection
13. Pelvic radiation
14. Spinal cord disease resulting in para- or quadri-plegia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage reduction in incontinence episodes on 4-day bladder diary
- Secondary Outcome Measures
Name Time Method 1. Number of subjects dry at end of study<br>2. Subjective satisfaction