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Comparison of the Clinical pregnancy outcomes of ovarian stimulation with hMG + rFSH or rFSH + rLH methods in infertile patients.

Phase 2
Conditions
Female infertility associated with anovulation.
Female infertility, unspecified
Registration Number
IRCT2016092720351N3
Lead Sponsor
Vice Chancellor or Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
140
Inclusion Criteria

aged 20-35 years;Tubal or unexplained infertility, regular menstruation cycle between 21 and 35 days; Normal function of uterus according to hysterosalpingography; hysteroscopy or transvaginal ultrasonography; Normal ovaries according to transvaginal ultrasonography during past 6 months prior to study and compatible with normal adnexa and normal ovarian anatomy; Serum FSH level less than 8 IU/l.

Exclusion Criteria

Patients with other ovulation disorders such as hypo and hyper-gonadotropic; hypo gonadism; hyper-prolactinemia; thyroid disorders; ovarian or adrenal neoplasms; Cushing syndrome; previous history of systemic diseases such as endocrine and metabolic disorders and a previous history of inappropriate ovarian response to stimulation with gonadotropins (poor responders), prior history of more than 3 unsuccessful IVF; any malformation of sexual organs were excluded

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Chemical pregnancy. Timepoint: two weeks after embryo transfers. Method of measurement: Blood test.;Clinical Pregnancy. Timepoint: three weeks after seeing sac fetus. Method of measurement: transvaginal sonography.;Live birth. Timepoint: after delivery. Method of measurement: Live birth.;Abortion. Timepoint: two weeks after embryo transfers. Method of measurement: transvaginal sonography.
Secondary Outcome Measures
NameTimeMethod
umber of oocyte. Timepoint: six day after treatment. Method of measurement: Transvaginal sonography.;Number of embryo. Timepoint: one day after oocyte pick up. Method of measurement: See under a microscope by a specialist in embryology.
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