MedPath

Ovarian Cancer Hemoscope Trial

Active, not recruiting
Conditions
Ovarian Neoplasms
Registration Number
NCT02811224
Lead Sponsor
Scripps Translational Science Institute
Brief Summary

This is a prospective, gold standard observational trial designed to enroll consecutive, consenting ovarian cancer patients for the purpose of determining sensitivity of an assay that detects circulating tumor DNA. This observational pilot trial will also be used to examine the genetic variants/mutations present in the tumor tissue DNA.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
Female
Target Recruitment
50
Inclusion Criteria

Case Group

  • Patients with ovarian cancer undergoing surgery (all stages)
  • Over 18 years old

Control Group

  • Patients with a benign gynecological condition undergoing surgery
  • Over 18 years old
Exclusion Criteria
  • Previous cancer diagnosis (all)
  • Radiation therapy before surgical treatment
  • Bone marrow transplant
  • Chemotherapy before surgical treatment
  • Invasive procedure resulting in damage to tissue (e.g., surgery, biopsy, thermal ablation) in the 7 days prior to baseline (pre-surgical) blood collection

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Sensitivity of an assay that detects circulating tumor DNA3 years
Secondary Outcome Measures
NameTimeMethod
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