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Allarity Therapeutics

🇺🇸United States
Ownership
Public
Employees
6
Market Cap
-
Website
http://www.allarity.com
Introduction

Allarity Therapeutics, Inc. engages in the development of drugs for personalized treatment of cancer guided by its proprietary Drug Response Predictor (DRP) technology. The company operates in two geographic areas: Denmark and the United States. The company was founded on April 4, 2021 and is headquartered in Boston, MA.

Clinical Trials

9

Active:3
Completed:3

Trial Phases

2 Phases

Phase 1:4
Phase 2:4

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (8 trials with phase data)• Click on a phase to view related trials

Phase 1
4 (50.0%)
Phase 2
4 (50.0%)

Study to Determine the Maximum Tolerated Dose (MTD) of PARPi 2X-121 Monotherapy and the MTD of Dovitinib in Combination With 2X-121 in Patients With Advanced Solid Tumors

Phase 1
Suspended
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2022-10-07
Last Posted Date
2025-05-07
Lead Sponsor
Allarity Therapeutics
Target Recruit Count
40
Registration Number
NCT05571969
Locations
🇺🇸

Carolina BioOncology, Huntersville, North Carolina, United States

🇺🇸

University Hospitals Cleveland Medical Center, Cleveland,, Ohio, United States

Anti-tumor Effect of Ixabepilone in Metastatic Breast Cancer (mBC) Selected by the Ixabepilone DRP.

Phase 2
Suspended
Conditions
Metastatic Breast Cancer
Interventions
First Posted Date
2021-03-12
Last Posted Date
2025-02-04
Lead Sponsor
Allarity Therapeutics
Target Recruit Count
60
Registration Number
NCT04796324
Locations
🇧🇪

Antwerp University Hospital, Antwerp, Edegem, Belgium

🇧🇪

Onze-Lieve-Vrouwziekenhuis, Aalst, Belgium

🇧🇪

Clin. Univ. Saint-Luc, Brussels, Belgium

and more 16 locations

Investigation of the Anti-tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian Cancer

Phase 2
Active, not recruiting
Conditions
Advanced Ovarian Cancer
Interventions
First Posted Date
2019-03-18
Last Posted Date
2025-05-08
Lead Sponsor
Allarity Therapeutics
Target Recruit Count
40
Registration Number
NCT03878849
Locations
🇺🇸

OU Health Stephenson Cancer, Oklahoma City, Oklahoma, United States

🇺🇸

Swedish Center for Research and Innovation, Seattle, Washington, United States

Clinical Pre-screening Protocol for Ovarian Cancer

Active, not recruiting
Conditions
Ovarian Cancer
First Posted Date
2019-03-18
Last Posted Date
2025-01-23
Lead Sponsor
Allarity Therapeutics
Target Recruit Count
60
Registration Number
NCT03877796
Locations
🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

OU Health Stephenson Cancer Center, Oklahoma City, Oklahoma, United States

🇺🇸

Swedish Center for Research and Innovation, Seattle, Washington, United States

and more 2 locations

Irofulven in AR-targeted and Docetaxel-Pretreated mCRPC Patients With Drug Response Predictor (DRP®)

Phase 2
Completed
Conditions
Metastatic Castration-Resistant Prostate Cancer Patients
Interventions
Combination Product: Prednisolone 10 mg
First Posted Date
2018-08-22
Last Posted Date
2025-01-23
Lead Sponsor
Allarity Therapeutics
Target Recruit Count
15
Registration Number
NCT03643107
Locations
🇩🇰

Rigshospitalet, Dept. Of Oncology, Copenhagen, Denmark

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News

Allarity Therapeutics Unveils Novel Predictive Tool for Daratumumab Response in Multiple Myeloma Patients

• Allarity Therapeutics has developed a new Drug Response Predictor (DRP®) for daratumumab that can identify multiple myeloma patients most likely to benefit from treatment, as presented at AACR 2025. • The daratumumab DRP® is based on 53 genes associated with treatment sensitivity or resistance, and has demonstrated ability to predict treatment outcomes and survival in clinical samples. • This marks Allarity's first DRP® for an antibody therapy, expanding beyond small-molecule drugs and positioning the company for potential strategic partnerships in precision oncology.

Allarity Therapeutics Advances Stenoparib for Ovarian Cancer with Phase 2 Trial Expansion

Allarity Therapeutics is expanding its Phase 2 clinical trial of stenoparib for advanced ovarian cancer, aiming to optimize dosing and patient selection.

Allarity Therapeutics' Stenoparib Shows Promise in Advanced Ovarian Cancer Phase 2 Trial

Allarity Therapeutics reports that two patients with advanced ovarian cancer have remained on stenoparib treatment for over 14 months in a Phase 2 trial.

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