Understanding the Public Impact on Dengue Vaccination Strategies in Yunnan Province, China: A Dynamic Transmission Modeling Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- Dengue Virus Serological Response (IgM and IgG Antibody Levels)
研究概览
简要总结
This study is a collaboration between the School of Public Health at Fudan University and the Xishuangbanna Center for Disease Control and Prevention in Yunnan Province, China. It aims to evaluate the public health impact of dengue vaccination strategies using dynamic transmission models. By simulating different vaccination scenarios, the study will assess the potential effectiveness and public health benefits of dengue vaccine introduction, providing scientific evidence to support local dengue prevention and control efforts.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 3 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Resident of Jinghong City, Xishuangbanna Prefecture
- •Aged 3 years and above
- •Able and willing to provide informed consent (or have legal guardian consent for minors)
- •Available for blood sample collection between May and August 2025
排除标准
- •Individuals with bleeding disorders or other contraindications to blood draw
- •Individuals currently diagnosed with acute dengue infection
结局指标
主要结局
Dengue Virus Serological Response (IgM and IgG Antibody Levels)
时间窗: From blood sample collection to the completion of laboratory analysis of dengue serology, serotype identification, and whole genome sequencing, from May to August 2025
次要结局
未报告次要终点
研究者
Yao, Ye
Associate Professor of Fudan University
Fudan University