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Understanding the Public Impact on Dengue Vaccination Strategies in Yunnan Province, China: A Dynamic Transmission Modeling Study

Active, not recruiting
Conditions
Dengue Vaccination Strategy Evaluation
Transmission Modeling of Dengue
Public Health Impact of Vaccination
Registration Number
NCT07206784
Lead Sponsor
Fudan University
Brief Summary

This study is a collaboration between the School of Public Health at Fudan University and the Xishuangbanna Center for Disease Control and Prevention in Yunnan Province, China. It aims to evaluate the public health impact of dengue vaccination strategies using dynamic transmission models. By simulating different vaccination scenarios, the study will assess the potential effectiveness and public health benefits of dengue vaccine introduction, providing scientific evidence to support local dengue prevention and control efforts.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
220
Inclusion Criteria
  • Resident of Jinghong City, Xishuangbanna Prefecture
  • Aged 3 years and above
  • Able and willing to provide informed consent (or have legal guardian consent for minors)
  • Available for blood sample collection between May and August 2025
Exclusion Criteria
  • Individuals with bleeding disorders or other contraindications to blood draw
  • Individuals currently diagnosed with acute dengue infection

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Dengue Virus Serological Response (IgM and IgG Antibody Levels)From blood sample collection to the completion of laboratory analysis of dengue serology, serotype identification, and whole genome sequencing, from May to August 2025
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Xishuangbanna Center for Disease Control and Prevention

🇨🇳

Jinghong, Yunnan, China

Xishuangbanna Center for Disease Control and Prevention
🇨🇳Jinghong, Yunnan, China

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