Phenotyping and Genotyping of Duffy Antigen
- Conditions
- Plasmodium Vivax
- Registration Number
- NCT05527119
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
Malaria remains the world's leading parasitic endemic. Almost half of the world's population lives in endemic areas. Many at-risk people in African countries remain without access to malaria control. Malaria kills approximately 400,000 people each year, most of whom are children under the age of 5 in Africa. Since 2005, an increasing number of Plasmodium vivax infections have been observed in Duffy-negative populations in South America and Africa, calling into question the essential role of the PvDBP-DARC interaction. The objective of the investigators is therefore to study and understand the invasion pathways used by Plasmodium vivax in Duffy-negative subjects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Major subjects
- with malaria and willing to have their blood samples analyzed for this research
- Subjects refusing to participate in the study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of blood samples tested (phenotype and genotype). 2 months later
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Service de Laboratoire de Parasitologie et Mycologie Médicale-PTM - CHU de Strasbourg - France
🇫🇷Strasbourg, France