Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects
Not Applicable
Completed
- Conditions
- Hyperglycemia, Postprandial
- Registration Number
- NCT04914416
- Lead Sponsor
- Fytexia
- Brief Summary
This study aims to evaluate and select the best combination of polyphenol and white kidney bean ingredients in the acute glycemic modulation after a complete meal by measuring blood glucose and insulin.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- Glycemia: 100-125mg/dL
- Both sexes
- Overweight BMI range (27-32)
- Age: 20-50 years old
Exclusion Criteria
- Metabolic/Chronical disease
- Menopausal women
- Being pregnant, breastfeeding or wanting to have a baby
- Former obese with a history of yoyo effect
- Have been involved in a weight loss program in the past 12 months or subjected to weight reduction surgery
- Having started or quit smoking, having a high alcohol consumption
- Have in the past been in a long-term antibiotherapy (1 month or more) and/or a regular antibiotherapy in the past 12 months
- Allergy to olive, artichoke, black currant, grapefruit, grape, white kidney bean, olive, pomegranate.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Acute change in glycemia in response to a meal, by measuring glucose concentration in the blood at different time points 8 hours
- Secondary Outcome Measures
Name Time Method Lipid profile evolution after a meal 8 hours Oxxidative stress variation after a meal, measured by oxidized/reduced glutathione (GSH/GSSG) 8 hours Acute change in insulinemia in response to a meal, by measuring insulin concentration in the blood at different time points 8 hours
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms of polyphenols and white kidney bean extracts influence postprandial glycemic control in NCT04914416?
How does OxxyneaGS compare to alpha-glucosidase inhibitors like acarbose in acute hyperglycemia management?
Which biomarkers correlate with blood glucose and insulin response to OxxyneaGS in light hyperglycemic subjects?
What adverse events are associated with polyphenol-based dietary supplements for glycemic regulation in clinical trials?
What are the potential synergistic effects of combining OxxyneaGS with GLP-1 receptor agonists for postprandial glucose control?
Trial Locations
- Locations (1)
UCAM
🇪🇸Murcia, Spain
UCAM🇪🇸Murcia, Spain