Determination of the Glycemic Index Values of 10 Cereal-based Products

Not Applicable

Completed

• Conditions: Low Glycemic Index (GI) Food; Pre Diabetes; Diabetes

• Registration Number: NCT06710743
• Lead Sponsor: PepsiCo Global R&D

Brief Summary

To determine the Glycemic index values for 10 cereal-based products

Detailed Description

To determine the Glycemic index values for 10 cereal-based products per international standard (ISO26642:2010) for glycemic index determination.

Study Timeline

• Study Start: 2024-07-01
• Primary Completion: 2024-09-27
• Study Completion: 2024-09-27
• Status Verified: 2024-11
• Study First Submitted: 2024-11-25
• Study First Submitted QC: 2024-11-26
• Last Update Submitted: 2024-11-26
• Study First Posted: 2024-11-28
• Last Update Posted: 2024-11-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• 10 healthy participants, male and female (non-pregnant, non-lactating) of mixed ethnicity, aged between 18 - 65 y
• BMI: 18 - 25.0 kg/m2 (bounds included)
• Non smokers
• Normal glucose tolerance (assessed by 50 gram oral glucose tolerance test performed within the last 30 days: fasting <6 mM, 2 hr glucose <7.8 mM)
• Stable weight and dietary habits. Normal eating patterns and no history of eating disorders or recent dieting
• Normal sleep patterns (ie. at least 6 hours of sleep per night)
• The participants are required to avoid alcohol and unusual levels of food intake and physical activity for the 24 hours before each test session.
• Absence of health conditions that would prevent fulfillment of study requirements as judged by the Investigator on the basis of medical history. Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.

Exclusion Criteria

• Food allergy or intolerance to the study ingredients (eg. gluten, etc.)
• Regularly taking prescription medication other than standard contraceptive medication
• Taking any medications known to affect glucose tolerance (eg. acetylsalicylic acid, thyroxin, vitamins and mineral supplements or drugs to treat hypertension or osteoporosis)
• Suffering from any illness or disease
• Following a restricted diet
• Smokers
• Eating disorders
• Abnormal glucose tolerance or known history of diabetes mellitus.
• Individuals currently participating in other acute metabolic studies
• Failure to meet any one of the inclusion criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Glycemic index (GI) values	Two hour test session per visit. Visits must be at least two days apart. Including Screening, the study duration is approximately four to eleven weeks depending on whether participants are available to be tested one, two or three times per week.	Comparison of Glycemic index (GI) values of 10 different cereal-based products and the reference food (glucose solution assigned GI=100 by definition)

Trial Locations

Locations (1)

Sydney University's Glycemic Index Research Service (SUGiRS); 🇦🇺 Sydney, New South Wales, Australia