A Prospective Randomised Comparison of Cold Snare Polypectomy Versus Cold Snare Pseudosuction Technique
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 112
- 试验地点
- 1
- 主要终点
- Complete macroscopic polyp eradication rate
研究概览
简要总结
Different modalities are employed to remove small colonic polyps which potentially harbour a cancer risk. But, they can all vary in their completeness of removal, safety and the histological quality and the gold standard technique has yet to be defined. A novel suction pseudopolyp technique has been described by Patullo et al and in their prospective study, 126 polyps measuring less than 10mm flat or sessile were removed by this method with 100% complete endoscopic resection and without any immediate or delayed complications. The aim of the investigators study is to compare this technique with the standard cold snare technique. Patients attending for a routine colonoscopy and found to have polyps measuring 37mm in size will be eligible and they will be randomised to the polypectomy technique. Patient demographics and polyp characteristics will be recorded. The primary outcome measured will be the macroscopic resection rate. The secondary outcome measures are abdominal pain, tenderness, bleeding and fever.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with small polyps 3-7 mm in size, flat or sessile found during colonoscopy
排除标准
- •Patients are less than 18 years old
- •Inadequate bowel preparation
- •On anticoagulants or clopidogrel
研究组 & 干预措施
conventional cold snare polypectomy
conventional cold snare polypectomy
干预措施: conventional cold snare polypectomy (Procedure)
Cold snare polypectomy with suction
Cold snare polypectomy with suction
干预措施: Cold snare polypectomy with suction (Procedure)
结局指标
主要结局
Complete macroscopic polyp eradication rate
时间窗: At time of polypectomy intervention
The primary outcome for this study is the polypectomy completion rate. This will be assessed both macroscopically and histologically. The analysis for statistical difference between the 2 techniques and abdominal symptoms will be compared by the Chi2 test for categorical data.
次要结局
未报告次要终点
