Hardwins - Squamous Cell Carcinoma Head & Neck (Surgery/RT)
- Conditions
- Carcinoma, Squamous Cell
- Registration Number
- NCT00188318
- Lead Sponsor
- University Health Network, Toronto
- Brief Summary
This study is examining the effects of increasing the dose of radiation given to treat head and neck cancer. Radiation doses to the primary cancer are higher than usually given; lymph glands of the neck will also be treated at a lower dose. Surgery on the lymph glands my be necessary in the future. Radiation treatments given in small fractions twice a day allows a higher dose to be delivered than if the treatment was given once a day. This study will enroll patients at three sequential increasing dose levels. Approximately 40 patients will be enrolled at each dose level.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 169
- Histologically proven squamous cell carcinoma
- Larynx & pharynx (except Nasopharyngeal carcinoma)
- Stage III & IV, but any stage hypopharynx
- Informed Consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Toxicities as per CTCAE 1 yr
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
Princess Margaret Hospital
🇨🇦Toronto, Ontario, Canada
Princess Margaret Hospital🇨🇦Toronto, Ontario, Canada