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临床试验/NCT07314034
NCT07314034
招募中
不适用

Facially Driven Digital Workflow for Esthetic and Functional Full-mouth Rehabilitation

Menoufia University1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2024年6月1日最近更新:

概览

阶段
不适用
状态
招募中
入组人数
10
试验地点
1
主要终点
Implant Stability

概览

简要总结

Participants with bite difficulties, smile dissatisfaction, and missing mandibular molars was rehabilitated using a fully digital, facially driven workflow. Integration of intraoral, facial, and CBCT data guided esthetic design, occlusion, and implant planning, resulting in precise alignment, functional occlusion, and esthetic restoration with veneers, zirconia crowns, TAD-assisted molar intrusion, and guided implants.

详细描述

This Prospective study describes the comprehensive digital management of patients presenting with anterior open bite, smile dissatisfaction, and missing mandibular molars. A 3D virtual patient model was created by integrating intraoral scans, facial scans, and CBCT imaging, enabling prosthetically driven planning for esthetic and functional outcomes. Treatment involved conservative anterior rehabilitation with lithium disilicate veneers, full-coverage monolithic zirconia crowns, TAD-assisted intrusion of extruded molars, and guided implant placement for missing mandibular molars. The fully digital, facially guided workflow allowed precise restoration positioning, occlusal harmony, and predictable functional and esthetic results, demonstrating the utility of integrated digital planning in complex full-mouth rehabilitation.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 20-45 years with partial or complete edentulism requiring full-mouth rehabilitation.
  • Patients with bite dysfunction, malocclusion, or esthetic concerns suitable for digital workflow treatment.
  • Adequate bone volume for implant placement or candidates for TAD-assisted tooth movement.
  • Willingness to undergo treatment using a fully digital, facially guided workflow and comply with follow-up visits.
  • Ability to provide informed consent.

排除标准

  • Systemic conditions contraindicating implant or surgical procedures (e.g., uncontrolled diabetes, immunosuppression).
  • Active oral infections or untreated periodontal disease.
  • Heavy smokers (\>10 cigarettes/day) or substance abuse.
  • History of head and neck radiation therapy or bisphosphonate use.
  • Pregnancy or breastfeeding.
  • Inability to comply with treatment or follow-up protocol.

结局指标

主要结局

Implant Stability

时间窗: 12 months post-treatment

Clinical assessment: Absence of implant mobility assessed manually and using opposing instrument pressure. Radiographic assessment: Periapical radiographs using the paralleling technique to evaluate peri-implant bone levels. Success criteria: No progressive peri-implant radiolucency and marginal bone loss ≤ 1.5 mm during the first year, in accordance with Albrektsson et al. success criteria.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohammed El-Sawy

Clinical Professor and principle investigator

Menoufia University

研究点 (1)

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