Testing for interactions between anaesthetic drugs

Phase 3

• Conditions: Patients who are undergoing any type of surgery that require general anaesthetic, intubation and the surgery duration is more than one hour.; Anaesthesiology - Anaesthetics; Surgery - Other surgery

• Registration Number: ACTRN12606000522516
• Lead Sponsor: Dr Doug Campbell

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-12-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1) American Society Anaesthesiology Grade (ASA) grade 1-3 (healthy or with mild or moderate but stable disease). 2) Surgery usually associated with minimal blood loss and expected to last at least 1.5hrs.

Exclusion Criteria

1) Contraindication to using reminfentanil or sevoflurane - including allergy and malignant hyperpyrexia2) inability to converse fluently in English.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bispectral Index (BIS) [Measured for the duration of surgery estimated 1 to 4 hours at 1 minute intervals.];Observer Assessment Sleep & Sedation (OASS) [Measured 5 min after every change in drug dosage.]

Secondary Outcome Measures

Name	Time	Method
Physiological - Blood Pressure and Pulse.[ 5 min intervals during the general anaesthetic estimated 1 to 4 hours.]