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Clinical Trials/NCT07181707
NCT07181707Not yet recruitingNot Applicable

Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a Cone Beam Computed Tomography Study

Central Hospital, Nancy, France1 site in 1 country200 target enrollmentStarted: October 1, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
200
Locations
1
Primary Endpoint
Maturation stages of the midpalatal suture

Study Overview

Brief Summary

Assessing the maturation of the mid-palatal suture is an essential criterion for orthodontic decision-making. However, from a CBCT according to Angelieri's classification , it remains difficult for the practitioner's untrained eye.

As profile teleradiographs are almost routinely performed in orthodontic check-ups, numerous studies have looked for a correlation between the stage of maturation of the palatal suture and that of the cervical vertebrae. Some have also looked for a link with mineralization of mandibular third or second molars according to Demirjian's classification.

These techniques would provide a reliable and reproducible method without the use of CBCT.

In our study, the investigators will be looking for a correlation with mineralization of the maxillary third molar according to Nolla's classification. The latter has become common in practice and easy to apply on an orthopantomogram.

This would simplify decision-making without the need for a CBCT, but by using the orthopantomogram which is already routinely performed during the assessment.

Detailed Description

The study is a non-interventional (observational) research involving the human person, research on existing data (retrospective study).

This study analyzes the maturation stage of the Midpalatal suture and the mineralization of the third left molar.

This is a comparative retrospective study of radiographs in three dimensions before any orthodontic treatment to study a potential correlation.

There is no control group but there are subgroups depending of the age of the patients.

Study Design

Study Type
Observational
Observational Model
Other
Time Perspective
Retrospective

Eligibility Criteria

Ages
9 Years to 40 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • No previous orthodontic or orthopedic treatment
  • At least the maxillary third left molar
  • No skeletal disability

Exclusion Criteria

  • Previous maxillofacial trauma
  • Dentofacial deformities
  • Endocrinological pathologies with implications for maxillofacial growth • - Syndromes
  • History of maxillofacial or orthognathic surgery
  • History of orthodontic treatment
  • Incomplete data or incomplete CBCT
  • Maxillary third left molar fracture/cavity/other deterioratedation

Outcomes

Primary Outcomes

Maturation stages of the midpalatal suture

Time Frame: One day

Stages according to Angelieri et al.

Third molar calcification

Time Frame: One day

Calcification's stages of the third left molar maxillary (from 0 to 10) according to Nolla.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Central Hospital, Nancy, France
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

VANDE VANNET Bart

Professor

Central Hospital, Nancy, France

Study Sites (1)

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